Efficacy of intrarticular steroid injection in osteoarthritis of the first carpometacarpal joint (CMCJ).

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2004-004591-37-GB

Enrollment

154

Registered

2005-02-17

Start date

2005-01-31

Completion date

Unknown

Last updated

2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the 1st carpometacarpal joint (CMCJ)

Interventions

Trade Name: DEPO-MEDRONE Product Name: METHYLPREDNISOLONE ACETATE 40mg Pharmaceutical Form: Solution for injection Trade Name: Marcain Product Name: Bupivocaine Hydrochloride 0.5% Pharmaceutical Form

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consecutive patients assessed by three specialist Hand Surgeons in their routine outpatient clinics. Consent Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Withdrawal of consent.

Design outcomes

Primary

Measure	Time frame
Main Objective: The aim of this study is to evaluate by a randomised control trial the efficacy of image guided injection into the 1st CMCJ of steroid/local anaesthetic versus local anaesthetic only in patients with osteoarthritis.;Secondary Objective: ;Primary end point(s): We have taken advice from the Trust Statistician and for a significant difference in pain scores to be detected (taken as a difference of 2 levels on a 7 point scale) 77 patients are required in each arm.	—

Measure

Time frame

Main Objective: The aim of this study is to evaluate by a randomised control trial the efficacy of image guided injection into the 1st CMCJ of steroid/local anaesthetic versus local anaesthetic only in patients with osteoarthritis.;Secondary Objective: ;Primary end point(s): We have taken advice from the Trust Statistician and for a significant difference in pain scores to be detected (taken as a difference of 2 levels on a 7 point scale) 77 patients are required in each arm.

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Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026