Photodynamic Therapy (PDT) vs Chemopeeling for the treatment of multiple actinic keratoses on the underarms

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2004-004258-26-AT

Enrollment

Registered

2005-05-19

Start date

2005-06-23

Completion date

Unknown

Last updated

2015-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Actinic Keratosis

Interventions

Product Name: Trichloroacetic acid Pharmaceutical Form: Cutaneous liquid INN or Proposed INN: Trichloroacetic Acid CAS Number: 76-03-9 Other descriptive name: TCA Concentration unit: % percent Concen

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients (at leat 50 years old) with multiple actinic keratoses on both underarms(at least 3/side) Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: -Immunsuppression -Reduced general health condition -Reduced renal function -Intolerance against aminolevulinic acid/ trichloroacetic acid (TCA) -Systemic administration of retinoids within the last 6 months -Current adminsitration of Vitamin-K antagonists

Design outcomes

Primary

Measure	Time frame
Main Objective: A comparison of two different therapeutic modalities (phototdynamic therapy with aminolevulinic acid vs. chemopeeling with trichloroacetic acid) in the treatment of multiple actinic keratoses on the underarms to determine the optimal treatment of this precancerous cuatanous condition of high prevalence. ;Secondary Objective: Side effects, tolerability the two therapies by the patients, cosmetical results of the two treatments;Primary end point(s): Primary endpoint is the count of healed actinic keratotic lesions after 52 weeks after treatment with each of the two therapies.	—

Measure

Time frame

Main Objective: A comparison of two different therapeutic modalities (phototdynamic therapy with aminolevulinic acid vs. chemopeeling with trichloroacetic acid) in the treatment of multiple actinic keratoses on the underarms to determine the optimal treatment of this precancerous cuatanous condition of high prevalence. ;Secondary Objective: Side effects, tolerability the two therapies by the patients, cosmetical results of the two treatments;Primary end point(s): Primary endpoint is the count of healed actinic keratotic lesions after 52 weeks after treatment with each of the two therapies.

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Countries

Austria

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026