The subjects in the study will be recruited via an advertisment and will not have a diagnos. We will include males with high consumption of alcohol, defines as 400 grams or more of 100% alcohol per week.
Conditions
Interventions
Trade Name: Remeron
Product Name: Organon
Pharmaceutical Form: Tablet
INN or Proposed INN: Remeron
Concentration unit: mg milligram(s)
Concentration type: equal
Concentration number: 30-
Pharmaceutica
Sponsors
Bo Söderpalm
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: High alcohol consumption, defined as 400 grams or more of 100% alcohol per week. Male gender. 18-65 years of age. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Ongoing psychiatric disorder. Ongoing somatic disorder of a serious kind. Medication. Ongoing drug abuse (other than alcohol and nicotine). Poor knowledge of the swedish language. Weight below 60 kg or overweight (BMI 30).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Is it possible to influence alcohol consumption by orally administer a drug with central adrenergic effects and effects on serotonergic transmission? Is it possible to obtain high compliance in a self-managed oral treatment for high alcohol consumption?;Secondary Objective: Is it possible to influence nicotine use and impulsivity by orally administer a drug with central adrenergic effects and effects on serotonergic transmission? Is it possible to relate differences in impulsivity and/or nicotine use in the subjects to their alcohol consumption?;Primary end point(s): Alcohol consumption | — |
Countries
Sweden
Outcome results
None listed