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Is there a role for Helicobacter pylori eradication in the treatment of laryngopharyngeal reflux? : A double blinded randomised case controlled clinical trial - H.pylori erradication in laryngopharyngeal rteflux.

Is there a role for Helicobacter pylori eradication in the treatment of laryngopharyngeal reflux? : A double blinded randomised case controlled clinical trial - H.pylori erradication in laryngopharyngeal rteflux.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
EU CTR
Registry ID
EUCTR2004-001633-42-GB
Enrollment
50
Registered
2005-02-15
Start date
2005-01-06
Completion date
Unknown
Last updated
2013-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

LARYNGOPHARYNGEAL ACID REFLUX

Interventions

Trade Name: ZOTON FASTAB Pharmaceutical Form: INN or Proposed INN: LANSOPRAZOLE CAS Number: 103577-45-3 Concentration unit: mg milligram(s) Concentration type: equal Concentration number: 30- Trade

Sponsors

NHS GRAMPIAN
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: LARYNGOPHARYNGEAL REFLUX AS PROVEN ON HISTORY AND FULL EXAMINATION Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: 1- UPPER AERODIGESTIVE TRACT MALIGNANCY 2- OTHER LARYNGEAL PATHOLOGY 3- PATIENTS CURRENTLY ON PROTON PUMP INHIBITOR THERAPY 4 - PATIENTS INVOLVED IN ANY OTHER CLINICAL TRIAL

Design outcomes

Primary

MeasureTime frame
Main Objective: TO ESTABLISH IF PATIENTS WITH LARYNGOPHARYNGEAL REFLUX HAVE HELICOBACTER PYLORI IN THERE DIGESTIVE TRACT;Secondary Objective: TO ESTABLISH IF ERADICATION OF HELICOBACTER PYLORI IMPROVES SUBJECTIVE SYMPTOMS AND OBJECTIVE SIGNS OF LARYNGOPHARYNGEAL REFLUX;Primary end point(s): 1- POSITIVE UREA BREATH TEST 2- REFLUX SYMPTOM INDEX SCORING SYSTEM PRE AND POST TREATMENT 3- REFLUX FINDINGS SCORING SYSTEM PRE AND POST TREATMENT—

Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026