Influence of postoperative acute kidney injury on one-year health-related quality of life of patients after cardiac surgery: prospective, observational study

Influence of postoperative acute kidney injury on one-year health-related quality of life of patients after cardiac surgery: prospective, observational study - LQL

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00041160

Enrollment

179

Registered

2026-07-29

Start date

2026-08-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N17.8

Interventions

Group 1: Arm 1: Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) who develop acute kidney injury (AKI), as defined by the KDIGO criteria, on three consecutive postoperative days w

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Written informed consent. All patients undergoing cardiac surgery with the use of cardiopulmonary bypass (CPB).

Exclusion criteria

Exclusion criteria: 1. Expected non-compliance with the study protocol. 2. Any form of renal replacement therapy (e.g., maintenance hemodialysis for chronic kidney disease stage G5d, peritoneal dialysis) or previous kidney transplantation. 3. Patients with acute kidney injury (AKI) diagnosed within 30 days prior to surgery according to the KDIGO criteria.

Design outcomes

Primary

Measure	Time frame
Investigation of the impact of postoperative acute kidney injury on health-related quality of life 365 days after cardiac surgery with cardiopulmonary bypass (CPB), as assessed by the Physical Component Summary (PCS) of the SF-36 Health Survey.	—

Secondary

Measure	Time frame
Comparison of health-related quality of life between patients with and without postoperative acute kidney injury at postoperative days 28, 90, and 180 following cardiac surgery with cardiopulmonary bypass (CPB), as assessed by the SF-36 Health Survey. Assessment of all-cause mortality up to 365 days postoperatively, determined through follow-up telephone interviews on postoperative days 28, 90, 180, and 365. Assessment of major cardiovascular complications requiring hospitalization, including stroke, acute myocardial infarction, new-onset cardiac arrhythmias, decompensated heart failure, and interventions for peripheral arterial disease (PAD), through follow-up telephone interviews on postoperative days 28, 90, 180, and 365. Assessment of infections requiring hospitalization through follow-up telephone interviews on postoperative days 28, 90, 180, and 365.	—

Measure

Time frame

Comparison of health-related quality of life between patients with and without postoperative acute kidney injury at postoperative days 28, 90, and 180 following cardiac surgery with cardiopulmonary bypass (CPB), as assessed by the SF-36 Health Survey. Assessment of all-cause mortality up to 365 days postoperatively, determined through follow-up telephone interviews on postoperative days 28, 90, 180, and 365. Assessment of major cardiovascular complications requiring hospitalization, including stroke, acute myocardial infarction, new-onset cardiac arrhythmias, decompensated heart failure, and interventions for peripheral arterial disease (PAD), through follow-up telephone interviews on postoperative days 28, 90, 180, and 365. Assessment of infections requiring hospitalization through follow-up telephone interviews on postoperative days 28, 90, 180, and 365.

—

Countries

Germany

Contacts

Public ContactTugce Dinc Dogan

Universitätsklinikum Bonn; Klinik und Poliklinik für Anästhesiologie und Operative Intensivmedizin

tugce.dinc-dogan@ukbonn.de+4917681428765

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026