Free Flap Surgery
Conditions
Interventions
Group 1: The OptiVOL project is designed as a retrospective observational study. Clinical data from patients who underwent elective free flap transfer for soft tissue reconstruction at the Unfallkrank
Sponsors
Unfallkrankenhaus Berlin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Free flap reconstruction performed in the following specialties: Oral and Maxillofacial Surgery Hand and Plastic Surgery
Exclusion criteria
Exclusion criteria: Pregnancy Ongoing therapeutic anticoagulation Age <18 years (or Age under 18 years)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the intraoperative fluid and catecholamine requirements during elective free flap reconstruction necessary to maintain haemodynamic homeostasis, as assessed by clinical parameters. Furthermore, the study will investigate the association between the extent of intraoperative fluid administration and catecholamine requirements and the incidence of postoperative flap loss, as well as the number of revision surgeries. The study parameters will be collected retrospectively from the hospital documentation system and analysed statistically. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints include the assessment of changes in arterial blood gas base excess and the measurement of inflammatory markers (leukocyte count and C-reactive protein [CRP]). For each of these parameters, the association with the extent of intraoperative fluid administration and catecholamine requirements will also be evaluated. The study parameters will be collected retrospectively from the hospital documentation system and analysed statistically. | — |
Countries
Germany
Contacts
Public ContactAdina Bathel
Unfallkrankenhaus Berlin
Outcome results
None listed