L40.9
Conditions
Interventions
Group 1: Observational study: Patients with moderate-to-severe psoriasis vulgaris who are scheduled to start or switch to systemic therapy. At therapy initiation (routine care), demographic and clinic
Sponsors
Klinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Female, male, and non-binary patients > 18 years of age with moderate to severe psoriasis vulgaris - Initiation or switch to systemic therapy as part of standard care - Ability and willingness to provide written consent to participate in the study
Exclusion criteria
Exclusion criteria: - Inability to give informed consent - Participation in another interventional study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concordance between Algorithm Recommendations and Physicians’ Treatment Decisions Time Point: T0: Initial treatment decision made during the study visit Measurement: Comparison of the treatment option suggested by the algorithm with the treatment selected by the treating dermatologists Statistical evaluation using the Cohen’s kappa coefficient (when comparing categories) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number and type of algorithmic treatment recommendations Time point: T0 Method: Documentation of prioritized treatment options using the scoring system 2. Identification of clinical factors relevant to decision-making Time point: T0 Method: Analysis of the parameters that lead to a change in treatment prioritization 3. Expert assessment of clinical plausibility Time point: after application to standardized patient vignettes Method: Structured assessment form (developed specifically for this study) | — |
Countries
Germany
Contacts
Public ContactChristina Pham
Klinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover
Outcome results
None listed