The Effect of Anesthesia and Analgesia Methods on Subjective Well-Being Following Elective Total Knee Arthroplasty (TKA)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00041059

Enrollment

Registered

2026-07-23

Start date

2011-03-21

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M17.9 Z96.65

Interventions

Group 1: Patients who undergo total knee replacement surgery receive the following anesthesia and analgesia protocol: Total intravenous general anesthesia with femoral nerve block and catheter placeme

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Primary total knee replacement - Adult men and women (age 18 and older) - ASA classification I–II (no or only mild systemic diseases)

Exclusion criteria

Exclusion criteria: - Impaired language comprehension - ASA classification III–IV (severe pre-existing systemic diseases) - Pre-existing neurological deficits - Blood clotting disorders - Infections at the puncture site - Previous surgeries in the area where the catheter will be inserted - Allergy to local anesthetics

Design outcomes

Primary

Measure	Time frame
The subject of this study is the effect of anesthesia and analgesia methods on patients’ subjective well-being following elective total knee arthroplasty. A standardized, structured questionnaire will be used to determine whether there are differences in patients’ well-being following two different anesthesia and analgesia techniques. The Anesthesiology Follow-up Questionnaire for Patients (ANP) used for this survey was first proposed in 1999 as part of a “Comprehensive Quality Management” initiative in the field of anesthesiology by the Professional Association of German Anesthesiologists. The anesthesiology follow-up questionnaires are distributed on the 1st and 2nd postoperative days in the general wards. The first questionnaire pertains to the patient’s condition on the day of surgery, the second to the condition on the 1st postoperative day, and the third to the condition on the 2nd postoperative day, resulting in an observation period of 48 hours.	—

Measure

Time frame

The subject of this study is the effect of anesthesia and analgesia methods on patients’ subjective well-being following elective total knee arthroplasty. A standardized, structured questionnaire will be used to determine whether there are differences in patients’ well-being following two different anesthesia and analgesia techniques. The Anesthesiology Follow-up Questionnaire for Patients (ANP) used for this survey was first proposed in 1999 as part of a “Comprehensive Quality Management” initiative in the field of anesthesiology by the Professional Association of German Anesthesiologists. The anesthesiology follow-up questionnaires are distributed on the 1st and 2nd postoperative days in the general wards. The first questionnaire pertains to the patient’s condition on the day of surgery, the second to the condition on the 1st postoperative day, and the third to the condition on the 2nd postoperative day, resulting in an observation period of 48 hours.

—

Secondary

Measure	Time frame
Improving the Quality of Treatment	—

Countries

Germany

Contacts

Public ContactMichael Przemeck

Medizinische Hochschule Hannover im Diakovere Annastift

Michael.Przemeck@diakovere.de+49 511 5354 399

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026