Effects of Blue-Light-Attenuating Lenses on Visual Comfort, Visual Function, and Digital Eye Strain Symptoms in Presbyopic and Non-Presbyopic Digital Device Users

Effects of Blue-Light-Attenuating Lenses on Visual Comfort, Visual Function, and Digital Eye Strain Symptoms in Presbyopic and Non-Presbyopic Digital Device Users - BLA-DES Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040945

Enrollment

Registered

2026-07-10

Start date

2022-05-23

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digital Eye Strain

Interventions

Group 1: Sequence A (n=30 subjects: 10 aged =34 years, 10 aged 35-45 years, 10 aged =46 years): All subjects wore untreated (UT) lenses for 14 days as a washout/adaptation period, then anti-reflective

Eligibility

Sex/Gender

All

Age

20 Years to 62 Years

Inclusion criteria

Inclusion criteria: Spherical equivalent refraction between -6.00 D and +4.00 D, with anisometropia =1.50 D; best-corrected monocular visual acuity =0.10 logMAR; presence of eye-strain symptoms (eye fatigue, headache, difficulty sustaining near work after digital device use, and difficulty concentrating during visual tasks); daily digital device use of at least 4 hours of computer use and 2 hours of smartphone or tablet use; written informed consent obtained prior to enrollment.

Exclusion criteria

Exclusion criteria: Glaucoma, age-related macular degeneration, strabismus, dry eye disease.

Design outcomes

Primary

Measure	Time frame
WHAT: Ocular straylight (log(s), measured with the C-Quant straylight meter) and contrast sensitivity. WHEN: Measured before and after each 12-day wearing period, for each of the three lens conditions (UT, AR, BLA). HOW: Objective clinical measurement using the C-Quant device for straylight; contrast sensitivity testing per standard clinical protocol.	—

Secondary

Measure	Time frame
WHAT: Digital eye strain symptoms (Italian CVSS17 questionnaire score) and subjective visual comfort (Numerical Rating Scales, NRS 0-10); accommodative microfluctuations, accommodative response, and accommodative facility in the youngest subgroup (=34 years); lens preference for purchase at study completion. WHEN: After each 12-day wearing period, for each of the three lens conditions. HOW: Validated questionnaire (CVSS17, Italian version) and NRS scales completed by subjects; objective accommodative measures assessed via autorefractor in the young-adult subgroup.	—

Measure

Time frame

WHAT: Digital eye strain symptoms (Italian CVSS17 questionnaire score) and subjective visual comfort (Numerical Rating Scales, NRS 0-10); accommodative microfluctuations, accommodative response, and accommodative facility in the youngest subgroup (=34 years); lens preference for purchase at study completion. WHEN: After each 12-day wearing period, for each of the three lens conditions. HOW: Validated questionnaire (CVSS17, Italian version) and NRS scales completed by subjects; objective accommodative measures assessed via autorefractor in the young-adult subgroup.

—

Countries

Italy

Contacts

Public ContactGiancarlo Montani

Department of Mathematics and Physics, University of Salento

giancarlo.montani@unisalento.it+393482404670

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026