F45.41
Conditions
Interventions
Group 1: Single observational cohort, no comparison group. All eligible patients with chronic pain (=3–6 months) who completed a standardized pre-treatment multidisciplinary assessment (SPMA) and were
data were analyzed retrospectively.
Sponsors
Charité – Universitätsmedizin Berlin
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Chronic pain persisting for at least 3–6 months, meeting eligibility according to the Ad Hoc Commission "Interdisciplinary Multimodal Pain Therapy" of the German Pain Society and the German OPS 8-918. Patients had to fulfil at least three of the following: (i) reduced quality of life or impaired ability to work/function in daily life; (ii) failure of prior unimodal treatment, surgery, or withdrawal; (iii) medication misuse or dependency; (iv) significant psychological or somatic comorbidities. Additional requirements: sufficient motivation for active participation, ability to walk at least 500 metres, suitability for group-based treatment, adequate German language proficiency, and absence of unresolved compensation or litigation conflicts.
Exclusion criteria
Exclusion criteria: Failure to meet the eligibility criteria above, including insufficient motivation for active participation, inability to walk at least 500 metres, unsuitability for group-based treatment, inadequate German language proficiency, or unresolved compensation or litigation conflicts. Final admission decisions were made during a weekly interdisciplinary team meeting based on predefined clinical inclusion criteria, with social and contextual factors considered.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WHAT: Three co-primary domains, change from baseline to post-treatment: (1) general/emotional well-being, (2) mental health-related quality of life, (3) physical activity. WHEN: At baseline (treatment start, T1) and post-treatment (discharge, T2). HOW: (1) Marburg Questionnaire on Habitual Well-Being (MFHW); (2) Veterans RAND 12 Mental Component Summary (VR-12 MCS); (3) International Physical Activity Questionnaire, Short Form (IPAQ-SF). Analyzed with Wilcoxon signed-rank tests, Bonferroni-adjusted p = 0.017. | — |
Secondary
| Measure | Time frame |
|---|---|
| Predictors of poor treatment response (lowest tertile of improvement per primary domain), assessed via baseline demographic, clinical, and psychosocial variables (age, sex, pain duration, baseline symptom severity, psychosocial burden) using logistic regression. Longitudinal trajectories across six outcome domains (the three primary domains plus pain intensity [NRS], physical health-related quality of life [VR-12 PCS], and the affective dimension of pain [SBL]) assessed at baseline (T1), discharge (T2), 3–6 months (T3), and 12 months (T4). Descriptive composite response (=50% improvement in =1 primary domain). | — |
Countries
Germany
Contacts
Public ContactSascha Treskatsch
Charité – Universitätsmedizin Berlin
Outcome results
None listed