Development of a mathematical model to describe the circadian rhythms of vital signs in patients who have been treated in an intensive care unit.

Development of a mathematical model to describe the circadian rhythms of vital signs in patients who have been treated in an intensive care unit. - Chrono ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040899

Enrollment

3000

Registered

2026-07-23

Start date

2026-05-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circadian rhythms in intensive care

Interventions

Group 1: A retrospective analysis of the circadian rhythms of patients treated in intensive care units between 2018 and 2025.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Intensive care treatment in one of the two interdisciplinary surgical intensive care units at TUM Klinikum Rechts der Isar.

Exclusion criteria

Exclusion criteria: Age < 18 years

Design outcomes

Primary

Measure	Time frame
The stability of the circadian rhythm is measured throughout the patient’s stay in the intensive care unit, as determined by mathematical methods such as chi-squared or Lomb-Scargle periodograms.	—

Secondary

Measure	Time frame
Survival during a stay in intensive care; duration and intensity of ventilation; organ replacement therapy; delirium	—

Countries

Germany

Contacts

Public ContactFridtjof Schiefenhövel

TUM School of Medicine and Health, Klinikum Rechts der Isar, Klinik für Anästhesiologie und Intensivmedizin

fridtjof.schiefenhoevel@tum.de+49 89 4140 5051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026