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The influence of GLP-1 (glucagon-like peptide)-modulating premedication on the incidence of postoperative complications.

The influence of GLP-1 (glucagon-like peptide)-modulating premedication on the incidence of postoperative complications. - GLP1-Periop

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00040848
Enrollment
2000
Registered
2026-07-03
Start date
2026-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T81.4 N17.8 F05.9

Interventions

Group 1: Retrospective, single-center cohort study. A retrospective analysis of data from patients who underwent surgery at University Hospital Aachen between January 1, 2019, and April 15, 2026, in

Sponsors

Uniklinkum RWTH Aachen
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: As this is a retrospective, single-center cohort study, there is no prospective recruitment and no formal a priori sample size calculation of the type used in interventional studies. The analysis includes all consecutive patients who underwent surgery at the participating clinics during the study period from January 1, 2019, to April 15, 2026, who meet the inclusion and exclusion criteria, and for whom an evaluable preoperative medication history and documentation of the endpoints are available.

Exclusion criteria

Exclusion criteria: Missing data regarding patients' prior medication, documentation of postoperative complications, or preoperative and postoperative blood values ??(see primary and secondary endpoints).

Design outcomes

Primary

MeasureTime frame
primary endpoint: occurrence of postoperative complications o Acute kidney injury o Postoperative delirium o Cardiac arrhythmias o Sepsis Assessment during the first four postoperative days.

Secondary

MeasureTime frame
Secondary endpoints: Modulation of inflammation o Leukocyte count pre- and postoperatively (measured in blood) o Blood glucose level pre- and postoperatively (measured in blood) Time of measurement: during routine preoperative laboratory testing and the first routine postoperative laboratory testing

Countries

Germany

Contacts

Public ContactJana Mossanen

Uniklinikum RWTH Aachen

jmossanen@ukaachen.de+492418036891

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026