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Optical Coherence Tomography in Pyoderma Gangrenosum: A Pilot Study to Develop Criteria for Initial Diagnosis and Treatment Response

Optical Coherence Tomography in Pyoderma Gangrenosum: A Pilot Study to Develop Criteria for Initial Diagnosis and Treatment Response

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00040622
Enrollment
40
Registered
2026-06-15
Start date
2026-03-24
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L88

Interventions

Group 1: Adult patients (= 18 years) with active ulceration due to pyoderma gangraenosum, venous leg ulcer, or hypertensive ischemic leg ulcer. All participants undergo non-invasive OCT examination of

Sponsors

Uniklinikum Erlangen, Hautklinik
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. At least 18 years of age at the time of consent. 2. Clinical suspicion or confirmed diagnosis of pyoderma gangrenosum or venous leg ulcer or hypertensive-ischemic ulcer (HYTILU) 3. Active ulceration at the time of study enrollment

Exclusion criteria

Exclusion criteria: 1. Severe pain that prevents an OCT examination.

Design outcomes

Primary

MeasureTime frame
Description of characteristic morphological features of pyoderma gangraenosum as assessed by optical coherence tomography (OCT), including epidermal, dermal, junctional, and vascular characteristics, evaluated qualitatively and semi-quantitatively.

Secondary

MeasureTime frame
Relative proportion of characteristic OCT features for PG prior to initiation of therapy Relative proportion of characteristic OCT features for PG during therapy Relative proportion of characteristic OCT features for PG after healing

Countries

Germany

Contacts

Public ContactMoritz Ronicke

Uniklinikum Erlangen, Hautklinik

moritz.ronicke@uk-erlangen.de0913135000

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026