Avoidance Behavior
Conditions
Interventions
Group 1: Deep TMS intervention using continuous theta-burst stimulation (cTBS) in a single session on one day.
Group 2: Deep TMS intervention using intermittent theta-burst stimulation (iTBS) in a sin
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Fluent in the German language - Capacity to give informed consent and legal capacity to act - Absence of a psychiatric disorder
Exclusion criteria
Exclusion criteria: - Current psychiatric disorder - Central nervous system neurological disorder - Pregnancy - Epilepsy, previous epileptic seizures, or a family history of epilepsy - Severe medical comorbidity - Non-removable ferromagnetic material near the stimulation site (e.g., implants or tattoos) - Withdrawal of informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in avoidance behavior between sham stimulation and inhibitory stimulation (cTBS), measured using an approach–avoidance task following each stimulation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Differences in avoidance behavior between the stimulation protocols (cTBS and sham) compared with excitatory stimulation (iTBS), assessed using an approach–avoidance task following each stimulation. 2. Differences in electroencephalography (EEG) correlates between the stimulation conditions, following each stimulation. 3. Differences in decision-making reaction time between the stimulation protocols during task performance, assessed using an approach–avoidance task following each stimulation. 4. Tokens gained during the Approach-Avoidance Task, following each stimulation. 5. Differences in the Positive and Negative Affect Scale (PANAS) following each stimulation. | — |
Countries
Germany
Contacts
Public ContactJuan Carlos Baldermann-Weiß
Universitätsklinikum Freiburg, Klinik für Psychiatrie und Psychotherapie
Outcome results
None listed