intermittent hypoxemia
Conditions
Interventions
Group 1: The study is designed as a prospective, monocentric, longitudinal, interventional pilot study. It will enroll 30 preterm infants with a gestational age of = 30 + 0 weeks. The aim of the study
no additional blood draws are performed specifically for this study.
To assess regulatory behavior, parents are provided with standardized, modified questionnaires regarding their child's crying, fee
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Gestational age = 30 0/7
Exclusion criteria
Exclusion criteria: Major congenital anomalies or inherited metabolic diseases or chromosomal anomalies that may have an adverse effect on breathing or ventilation; infants with primary palliative care, families without sufficient knowledge of the German language to provide informed consent and fill out a questionnaire.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| - Association of intermittent hypoxemia episodes, abdominal contractions and noises with sleep stages - Quantification of external/ environmental factors in the NICU and their impact on intermittent hypoxemia (e.g. duration of bonding) - Stress burden, measured as blood cortisol levels - Evaluation of regulatory disorder problems (after discharge) in association with intermittent hypoxemia - Parental burden caused by behavioral mechanisms (i.e., “preemie grunts”) | — |
Primary
| Measure | Time frame |
|---|---|
| -Objective quantification and characterization of intermittent hypoxemia episodes and associated (vocal) sounds at two time points during hospitalization (postmenstrual age (PMA): 32 and 36 weeks) and at one time point after discharge (at 4 months corrected age) -Vocal classification of intermittent hypoxemia | — |
Countries
Germany
Contacts
Public ContactLeonie Paciello und Kriszta Molnar
Universitätsklinikum Tübingen
Outcome results
None listed