K72.9
Conditions
Interventions
Group 1: Retrospective cohort study without intervention arms.
Group comparisons are based on postoperative outcome (uneventful course, Early Allograft Dysfunction (EAD), Primary Non-Function (PNF), s
Sponsors
Institut für Pathologie, Universitätsklinikum Essen
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Liver transplants performed at the University Hospital Essen between 01 January 2010 and 31 December 2019 • Availability of histological frozen section findings of the donor organ (Institute of Pathology, University Hospital Essen) • Availability of clinical follow-up data (Department of General, Visceral and Transplantation Surgery, University Hospital Essen)
Exclusion criteria
Exclusion criteria: • Missing histological frozen section findings of the donor organ • Missing clinical follow-up data of the recipient • Liver transplantations performed outside the defined study period (before 01 January 2010 or after 31 December 2019)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of early complications within 7 days after liver transplantation, defined as: • Early Allograft Dysfunction (EAD): AST (GOT) or ALT (GPT) >2000 U/L, or total bilirubin >10 mg/dL, or INR >1.6 • Primary Non-Function (PNF): Primary graft failure requiring retransplantation or resulting in patient death • Unremarkable course: Absence of the above-mentioned criteria within the first 7 days after transplantation | — |
Secondary
| Measure | Time frame |
|---|---|
| • 1-year survival after liver transplantation • Correlation between histological and surgical assessment of steatosis • Influence of additional donor and recipient parameters on outcome | — |
Countries
Germany
Contacts
Public ContactFinn Wichmann
Institut für Pathologie, Universitätsklinikum Essen
Outcome results
None listed