Changes in the Disc Height Index and radiographic stability following single-segment microsurgical sequestrectomy for lumbar disc herniation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040457

Enrollment

250

Registered

2026-06-30

Start date

2026-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M51.1

Interventions

Group 1: Retrospective observational study: Patients with lumbar disc herniation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: o Age = 18 years o Lumbar disc herniation

Exclusion criteria

Exclusion criteria: o Multiple trauma (ISS > 16) o Surgery for tumors, infections, or revision procedures o Incomplete diagnostic workup

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study is the change in the modified disc height index (mDHI) between preoperative imaging and the radiological follow-up at 12 months.	—

Secondary

Measure	Time frame
Secondary endpoints include the occurrence of radiographic signs of segmental instability, including sagittal translations, changes in segmental angular relationships, retrolisthesis or spondylolisthesis, as well as degenerative changes in the intervertebral disc and adjacent structures.	—

Countries

Germany

Contacts

Public ContactKatharina Blanka Jäckle

Universitätsmedizin Göttingen

katharina.jaeckle@med.uni-goettingen.de+495513962462

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026