A clinical comparison of two different fabrication methods with regard to the accuracy of all-ceramic restorations. A prospective, randomized controlled clinical trial.

A clinical comparison of two different fabrication methods with regard to the accuracy of all-ceramic restorations. A prospective, randomized controlled clinical trial. - Ivoclar 2.0

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040438

Enrollment

Registered

2026-05-28

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Evaluation of two different fabrication methods for the production of all-ceramic restorations

Interventions

Group 1: Participants allocated to Arm 1 receive definitive all-ceramic restorations fabricated using a conventional analog workflow. After informed consent and baseline clinical assessment, treatment

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Proficiency in German - Age 18 or older - Capacity to give consent - Signed informed consent form - Completion of any prior treatment from a previous study

Exclusion criteria

Exclusion criteria: - Painful TMJ - Pregnancy

Design outcomes

Primary

Measure	Time frame
The primary endpoint is the accuracy of definitive all-ceramic restorations fabricated using either an analog or a digital workflow. Accuracy is assessed by two parameters: proximal contact in millimeters and marginal fit in millimeters. These parameters are evaluated after definitive placement and occlusal adjustment of the restorations. The intraoral situation is documented clinically and by intraoral scanning or conventional impression-taking, followed by quantitative analysis. Additional clinical follow-up examinations are scheduled at 6, 12, 24 and 36 months after placement.	—

Measure

Time frame

The primary endpoint is the accuracy of definitive all-ceramic restorations fabricated using either an analog or a digital workflow. Accuracy is assessed by two parameters: proximal contact in millimeters and marginal fit in millimeters. These parameters are evaluated after definitive placement and occlusal adjustment of the restorations. The intraoral situation is documented clinically and by intraoral scanning or conventional impression-taking, followed by quantitative analysis. Additional clinical follow-up examinations are scheduled at 6, 12, 24 and 36 months after placement.

—

Secondary

Measure	Time frame
1. Marginal integrity of the restorations (overall) 2. Interproximal contacts of the restorations (overall) 3. Occlusal contacts of the restorations (overall) 4. Fabrication time: digital vs. analog (clinical treatment time and (Laboratory time as a total value) 5. Changes in the Oral Health Impact Profile (OHIP)-49 at 6, 12, 24, and 36 months following the placement of the denture.	—

Countries

Germany

Contacts

Public ContactElisabeth Prause

Charité

elisabeth.prause@charite.de+4930450662557

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026