Continuous mechanical cooling attenuates short-term thermophysiological adaptation in office environments: a randomized parallel-group intervention

Continuous mechanical cooling attenuates short-term thermophysiological adaptation in office environments: a randomized parallel-group intervention - FRvsAC

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040431

Enrollment

Registered

2026-05-27

Start date

2023-06-05

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults exposed to indoor thermal environments under sedentary office conditions.

Interventions

Group 1: Free-running office exposure (FR): Participants were exposed to a naturally varying office environment during ten weekday intervention sessions over three consecutive weeks. Participants were

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy sedentary adults without known cardiovascular, metabolic, or thermoregulatory disorders; no regular habitual exposure to air-conditioned environments; ability to participate in repeated office-based thermal exposure sessions; willingness to comply with study procedures.

Exclusion criteria

Exclusion criteria: Smoking, cardiovascular disease, diabetes, chronic illness, regular medication use affecting thermoregulation or cardiovascular function, pregnancy, acute infection, or inability to complete repeated heat exposure sessions.

Design outcomes

Primary

Measure	Time frame
Primary outcome: PRE-to-POST change in late-phase core body temperature (CBT) drift during standardized heat-stress testing. Late-phase CBT drift was defined as the change in mean CBT between the pre-lunch reference window (12:15–12:30) and the final 15 minutes of the experimental session (16:15–16:30). CBT was measured continuously using ingestible telemetry pills (BodyCAP eCelsius Performance).	—

Measure

Time frame

Primary outcome: PRE-to-POST change in late-phase core body temperature (CBT) drift during standardized heat-stress testing. Late-phase CBT drift was defined as the change in mean CBT between the pre-lunch reference window (12:15–12:30) and the final 15 minutes of the experimental session (16:15–16:30). CBT was measured continuously using ingestible telemetry pills (BodyCAP eCelsius Performance).

—

Secondary

Measure	Time frame
Secondary outcomes included: Distal and proximal skin temperature drift (ankle and neck skin temperature) Heart rate and heart rate variability indices (RMSSD, HF power, LF/HF) Blood pressure responses (SBP, DBP, MAP, PP) Thermal sensation, thermal comfort, and thermal preference questionnaires Physiological measurements were collected during standardized PRE and POST heat-stress testing sessions before and after the ten-day intervention period.	—

Measure

Time frame

Secondary outcomes included: Distal and proximal skin temperature drift (ankle and neck skin temperature) Heart rate and heart rate variability indices (RMSSD, HF power, LF/HF) Blood pressure responses (SBP, DBP, MAP, PP) Thermal sensation, thermal comfort, and thermal preference questionnaires Physiological measurements were collected during standardized PRE and POST heat-stress testing sessions before and after the ten-day intervention period.

—

Countries

Germany

Contacts

Public ContactBilge Kobas

Technical University of Munich

bilge.kobas@tum.de+4915221348197

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026