ADAPT (Adaptive Digital Approaches to Well-Being Promotion Trial): A three-armed randomized controlled trial evaluating the efficacy of two personalized, transdiagnostic mental health products

ADAPT (Adaptive Digital Approaches to Well-Being Promotion Trial): A three-armed randomized controlled trial evaluating the efficacy of two personalized, transdiagnostic mental health products - ADAPT

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040429

Enrollment

420

Registered

2026-06-11

Start date

2026-03-12

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General perceived stress, Mental well-being, Everyday psychological burden

Interventions

Group 1: HelloBetter MindFIT, an online programme for stress management and psychological well-being support. It is recommended to complete approximately one exercise per day or one module per week. A

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Sufficient German language skills (min. C1 level) Access to a smartphone (min. Android 13 or iOS 18) Sufficient computer and internet skills Internet access

Exclusion criteria

Exclusion criteria: Substantial suicide risk (BDI-II Item 9 > 1)

Design outcomes

Primary

Measure	Time frame
Perceived Stress Scale (PSS-10; Schneider et al., 2020), measures the degree of perceived stress in everyday life. Collected at 6 weeks post randomisation (T1). An uncontrolled follow-up of is conducted 3 months after randomisation.	—

Secondary

Measure	Time frame
Well-being (composite score) at 6 weeks post randomisation (T1): WHO Well-Being Index (WHO-5; Brähler et al., 2007) to assesses subjective well-being, and Short Warwick-Edinburgh Mental Well-Being Scale (SWEMWBS; Peitz, Thom, et al., 2024) for mental well-being. Optimistic self-beliefs to cope with problems at 6 weeks post randomisation (T1): General Self-Efficacy Scale (GSES; Schwarzer & Jerusalem, 1999) Depressive symptoms over the last two weeks at 6 weeks post randomisation (T1): Patient Health Questionnaire-9 (PHQ-9; Löwe et al., 2002) Anxiety symptoms over the last two weeks at 6 weeks post randomisation (T1): Generalized Anxiety Disorder-7 (GAD-7; Löwe et al., 2008) An uncontrolled follow-up of all endpoints is conducted 3 months after randomisation.	—

Measure

Time frame

Well-being (composite score) at 6 weeks post randomisation (T1): WHO Well-Being Index (WHO-5; Brähler et al., 2007) to assesses subjective well-being, and Short Warwick-Edinburgh Mental Well-Being Scale (SWEMWBS; Peitz, Thom, et al., 2024) for mental well-being. Optimistic self-beliefs to cope with problems at 6 weeks post randomisation (T1): General Self-Efficacy Scale (GSES; Schwarzer & Jerusalem, 1999) Depressive symptoms over the last two weeks at 6 weeks post randomisation (T1): Patient Health Questionnaire-9 (PHQ-9; Löwe et al., 2002) Anxiety symptoms over the last two weeks at 6 weeks post randomisation (T1): Generalized Anxiety Disorder-7 (GAD-7; Löwe et al., 2008) An uncontrolled follow-up of all endpoints is conducted 3 months after randomisation.

—

Countries

Germany

Contacts

Public ContactDavid Daniel Ebert

Technische Universität München

david.daniel.ebert@tum.de+49 (0)89 / 289 24551

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026