Optimization of the Treatment Pathway for Transcatheter Aortic Valve Implantation (TAVI)

Optimization of the Treatment Pathway for Transcatheter Aortic Valve Implantation (TAVI) - ASPIRE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040428

Enrollment

5000

Registered

2026-05-21

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I35.2

Interventions

Group 1: In die retrospektive Baseline-Kohorte werden ca. 2000 erwachsene Patient:innen (beide Geschlechter) eingeschlossen, die zwischen August 2024 und August 2026 (vor der Implementierung des optim

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - planned elective TAVI at the DHZC - ability to consent - written consent

Exclusion criteria

Exclusion criteria: - Age < 18 years - Urgent or emergency procedures - Severe cognitive impairment - Legal guardianship - Life expectancy < 1 year - Insufficient language proficiency to independently utilize study information and standardized questionnaires

Design outcomes

Primary

Measure	Time frame
Total length of hospital stay in the context of elective TAVI treatment, before and after the implementation of an optimized treatment pathway.	—

Secondary

Measure	Time frame
o Length of ICU stay o Procedural and post-procedural complications according to VARC-3 o All-cause mortality at 90 days and 12 months o Readmissions at 90 days and 12 months Patient-Reported Outcomes (PROMs) o Disease-specific health status: KCCQ-12 o Generic health-related quality of life and function: PROMIS-Global Health and Physical Function o Patient satisfaction: CSQ-8 Process and Implementation Parameters o Pathway adherence; time of discharge o Usage parameters of the GetReady platform o Staff satisfaction and perceived process quality	—

Measure

Time frame

o Length of ICU stay o Procedural and post-procedural complications according to VARC-3 o All-cause mortality at 90 days and 12 months o Readmissions at 90 days and 12 months Patient-Reported Outcomes (PROMs) o Disease-specific health status: KCCQ-12 o Generic health-related quality of life and function: PROMIS-Global Health and Physical Function o Patient satisfaction: CSQ-8 Process and Implementation Parameters o Pathway adherence; time of discharge o Usage parameters of the GetReady platform o Staff satisfaction and perceived process quality

—

Countries

Germany

Contacts

Public ContactAxel Unbehaun

Deutsches Herzzentrum der Charité

axel.unbehaun@dhzc-charite.de+49 30 4593 2533

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026