Changes in respiratory and infrahyoid muscles and the development of secondary dysphagia in critically ill patients with mechanical ventilation (ChaRI-Dy).

Changes in respiratory and infrahyoid muscles and the development of secondary dysphagia in critically ill patients with mechanical ventilation (ChaRI-Dy). - ChaRI-Dy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040310

Enrollment

198

Registered

2026-05-22

Start date

2026-05-26

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R13

Interventions

Group 1: Critically-ill patients receive a maximum of three ultrasound exams to evaluate muscle changes in the diaphragm, rectus femoris, sternocleidomastoid and omohyoid muscle

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Intubation that is expected to exceed 72 hours of mechanical ventilation

Exclusion criteria

Exclusion criteria: - Neurological diseases which are associated with dysphagia - Expected mechanical ventilation less than 72 hours - Intubation after more than 5 days of ICU admission - Pre-existing dysphagia - If transferred from another hospital/ICU: Mechanical ventilation longer than 24 hours before admission to our hospital - Pre-existing tracheostomy - History of mechanical ventilation longer than 7 days in the past 6 months - Pregnancy - Tumor or other pathological changes in throat (incl. esophagus and trachea), head and face which are associated with dysphagia - Diaphragm paralysis or hernia - Rip fractur - Body-Mass-Index =40 - Radiation therapy on the upper body (cheast, head/face, throat) before or during hospital admission - Any situation which makes an ultrasound and/or dysphagia screening/evaluation impossible - Percutaneous Endoscopic Gastrostomy (PEG) or Percutaneous Endoscopic Jejunostomy (PEJ) - Non-German speaking patients

Design outcomes

Primary

Measure	Time frame
Endpoint (what): secondary dysphagia (nominal: yes/no) When: after extubation or tracheostomy How: Dysphagia screening/swallowing exam by trained specialist during the clinical routine	—

Countries

Germany

Contacts

Public ContactSindy Albrecht

Universitätsklinikum Hamburg-Eppendorf

si.albrecht@uke.de+49 152 228 16 270

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026