M00.9
Conditions
Interventions
Group 1: No study-specific examinations or interventions will be performed. Data will be collected retrospectively from electronic medical records of patients who underwent diagnostic joint aspiration
Sponsors
MUM Muskuloskelettales Universitätszentrum München, Klinik für Orthopädie und Unfallchirurgie, Campus Großhadern, LMU Klinikum
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The data collected retrospectively consists of findings from diagnostic joint aspirations obtained as part of routine clinical practice. These include biochemical, cytological, and microbiological parameters of the synovial fluid, as determined by standard procedures and documented in the patient’s medical record. In addition, information from the patient record (from the KAS) regarding the detection of microbiological pathogens in the synovial fluid, prior antibiotic therapy, intraoperative samples, as well as the clinical course and outcome (e.g., revision surgeries, mortality) is collected. The study period covers the years 2015 through 2025
Exclusion criteria
Exclusion criteria: Patients who have previously received antibiotic therapy Patients who have undergone multiple revisions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic significance of the laboratory chemical and cytological parameters of joint puncture obtained as part of clinical routine with regard to the presence of a septic process, defined by the microbiological detection of pathogens from the joint aspirate. | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of prior antibiotic therapy on • the biochemical and cytological parameters of the joint aspiration • the microbiological test results of the joint aspirate. Correlation between the microbiological results of the joint aspiration and samples taken intraoperatively, provided that surgery was performed. Correlation between the findings of the joint aspiration and the clinical outcome, defined by • the necessity of surgical intervention or revision surgery • mortality in the subsequent course. Exploratory analysis of possible differences • between different joints • as well as between native and arthroplastied joints. | — |
Countries
Germany
Contacts
Public ContactKathrin Pfahl
MUM Muskuloskelettales Universitätszentrum München, Klinik für Orthopädie und Unfallchirurgie, Campus Großhadern, LMU Klinikum
Outcome results
None listed