Effects of CPAP Therapy and Adaptive Servo-Ventilation on Periodic Limb Movements During Sleep

Effects of CPAP Therapy and Adaptive Servo-Ventilation on Periodic Limb Movements During Sleep - ECAP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040253

Enrollment

150

Registered

2026-05-12

Start date

2024-02-28

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G25.80

Interventions

Group 1: Patients with central sleep apnea and an indication for adaptive servo-ventilation therapy will undergo polysomnographic assessment of limb movements and respiratory parameters during diagnos

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Diagnosis of central sleep apnea requiring treatment Indication for adaptive servo-ventilation therapy Signed patient information and informed consent form

Exclusion criteria

Exclusion criteria: Lack of capacity to provide informed consent Contraindication to adaptive servo-ventilation therapy

Design outcomes

Primary

Measure	Time frame
PLMS index during the diagnostic night as well as during CPAP and ASV nights, assessed using polysomnography	—

Secondary

Measure	Time frame
Long-term effects of PLMS on patient-reported outcome measures (PROMs: fatigue, depression, daytime sleepiness, quality of life) in patients receiving ASV therapy, assessed annually at baseline and during the 5-year follow-up period using questionnaires (Fatigue Severity Scale, Beck Depression Inventory, Epworth Sleepiness Scale, EuroQol-5D)	—

Countries

Germany

Contacts

Public ContactAnett Lindner

Universitätsklinikum Regensburg Klinik und Poliklinik für Innere Medizin II

anett.lindner@ukr.de+49 941 944 7265

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026