Effects of different ventilation strategies on right ventricular function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040079

Enrollment

Registered

2026-04-23

Start date

2026-05-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J80

Interventions

Group 1: A total of 47 mechanically ventilated patients will be included. In all cases, a clinically indicated computed tomography (CT) scan of the thorax has been performed in accordance with the sta

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Written informed consent provided by the patient or their legal representative Analgosedated patients receiving mechanical ventilation Presence of a central venous catheter and an arterial catheter Hemodynamic stability under intensive care treatment (mean arterial pressure = 65 mmHg, cardiac output = 4.5 L/min/m² body surface area) Clinically indicated requirement for computed tomography of the thorax

Exclusion criteria

Exclusion criteria: Congenital cardiac malformations, severe valvular dysfunction, or severe arrhythmias Life expectancy of less than 24 hours Prior surgical interventions involving the organs under investigation

Design outcomes

Primary

Measure	Time frame
Right ventricular end-diastolic volume as determined by three-dimensional echocardiography, in comparison with two-dimensional echocardiography and CT-based volumetric analysis.	—

Secondary

Measure	Time frame
Effects of different mechanical ventilation strategies on right ventricular function.	—

Countries

Germany

Contacts

Public ContactAlice Marguerite Conrad

Klinik für Anästhesiologie und operative Intensivmedizin Universitätsmedizin Mannheim

alice.conrad@umm.de+4962138374628

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026