Influence of a nurse-led nutritional assessment and individual nutritional adaptation on the clinical course of enterally fed neurological/neurosurgical early rehabilitation patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00040062

Enrollment

130

Registered

2026-07-08

Start date

2026-08-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I60-I69

Interventions

Group 1: **Arm 1: Control Group (Standard Care Prior to Implementation of the Intervention)** The control group will be prospectively and consecutively recruited during the first study phase (control

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age =18 years Primary neurological or neurosurgical diagnosis (ICD-10-GM: I60–I69, S06; optionally G00–G99 according to study protocol) Requirement for enteral nutrition via feeding tube (e.g. PEG, PEJ, nasogastric or nasojejunal tube) Expected hospital length of stay of at least 7 days Written informed consent from the patient or legal representative

Exclusion criteria

Exclusion criteria: Age below 18 years No requirement for enteral nutrition (adequate oral nutrition possible) Expected hospital length of stay of less than 7 days Palliative situation with primarily symptom-oriented treatment Lack of informed consent from the patient or legal representative Participation in another interventional study with potential influence on nutritional status or functional outcomes

Design outcomes

Primary

Measure	Time frame
Primary Endpoint Change in functional recovery, measured using the Early Rehabilitation Barthel Index (ERBI; Früh-Reha-Barthel Index according to Schönle). T0: Baseline (1 week after admission) T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized assessment using the Early Rehabilitation Barthel Index (ERBI; score range 0–125 points).	—

Secondary

Measure	Time frame
Secondary Endpoints 1. Nutritional risk measured using Nutritional Risk Screening 2002 (NRS-2002) T0: within 72 hours of admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized screening using NRS-2002. 2. Malnutrition status measured using Global Leadership Initiative on Malnutrition (GLIM) criteria T0: within 72 hours of admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized diagnostic assessment using GLIM criteria. 3. Body weight / Body Mass Index (BMI) T0: admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized body weight assessment (calibrated bed scale) and BMI calculation. 4. Nosocomial infections Continuously assessed during hospitalization (T0–T2) Assessment method: Assessment according to Centers for Disease Control and Prevention (CDC) criteria using clinical documentation and microbiological findings. 5. Enteral feeding tolerance (diarrhea, constipation, vomiting) Daily during hospitalization Summarized analysis at T2 Assessment method: Standardized nursing documentation using predefined criteria. 6. Energy and protein target achievement Documented daily Evaluated weekly Final analysis at T2 Assessment method: Comparison of calculated nutritional requirements versus actual delivered intake (kcal/day; g protein/day). 7. Length of hospital stay T2 (at discharge) Assessment method: Number of inpatient treatment days according to medical records. Exploratory Endpoint In-hospital mortality Continuously assessed during hospitalization until T2 Assessment method: Clinical documentation.	—

Measure

Time frame

Secondary Endpoints 1. Nutritional risk measured using Nutritional Risk Screening 2002 (NRS-2002) T0: within 72 hours of admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized screening using NRS-2002. 2. Malnutrition status measured using Global Leadership Initiative on Malnutrition (GLIM) criteria T0: within 72 hours of admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized diagnostic assessment using GLIM criteria. 3. Body weight / Body Mass Index (BMI) T0: admission T1: 3 weeks after admission T2: prior to discharge Assessment method: Standardized body weight assessment (calibrated bed scale) and BMI calculation. 4. Nosocomial infections Continuously assessed during hospitalization (T0–T2) Assessment method: Assessment according to Centers for Disease Control and Prevention (CDC) criteria using clinical documentation and microbiological findings. 5. Enteral feeding tolerance (diarrhea, constipation, vomiting) Daily during hospitalization Summarized analysis at T2 Assessment method: Standardized nursing documentation using predefined criteria. 6. Energy and protein target achievement Documented daily Evaluated weekly Final analysis at T2 Assessment method: Comparison of calculated nutritional requirements versus actual delivered intake (kcal/day; g protein/day). 7. Length of hospital stay T2 (at discharge) Assessment method: Number of inpatient treatment days according to medical records. Exploratory Endpoint In-hospital mortality Continuously assessed during hospitalization until T2 Assessment method: Clinical documentation.

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Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026