Energy-Drinks - Unexplored Long-Term Cardiovascular Alterations in TEens and TwEens-Study (EDUCATE-II)

Energy-Drinks - Unexplored Long-Term Cardiovascular Alterations in TEens and TwEens-Study (EDUCATE-II) - EDUCATE-II

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00040046

Enrollment

Registered

2026-05-21

Start date

2026-07-14

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I51.6

Interventions

Group 1: "High chronic" ED consumers (=4 ED-days/week since =12 months, caffeine intake from EDs of =3 mg/kg on the day of consumption), aged =14 and =21 years Group 2: no ED-consumption, aged =14 a

Eligibility

Sex/Gender

All

Age

14 Years to 21 Years

Inclusion criteria

Inclusion criteria: Inclusion in the case group (=4 ED-days/week for =12 months, caffeine intake from EDs of =3 mg/kg on the day of consumption) or in the control group (no ED consumption)

Exclusion criteria

Exclusion criteria: Age 21 years Known pre-existing health conditions that may affect cardiovascular function, regular intake of medications and/or drugs that may affect cardiovascular function, current pregnancy, acute infection

Design outcomes

Primary

Measure	Time frame
BMI body fat percentage carotid intima-media thickness 24h systolic/diastolic blood preassure interventricular septum thickness LDL cholesterol HbA1c VO2max	—

Secondary

Measure	Time frame
ED-consumption behaviour, caffeine-consumption behaviour, pre-existing health conditions, Prevalence of adverse physical events, medication/drug use, socioeconomic status, education status, DAST-10 score, WHO-5, sleep duration, sleep quality, MEDAS score, KIDMED score, MET minutes per week, adherence to WHO guidelines on physical activity and sedentary behaviour, screen time Height, weight, waist circumference, lean body mass, Heart rhythm, electrical axis, heart rate, Sokolow-Lyon index, presence of cardiac arrhythmias, systolic/diastolic/central blood pressure, pulse wave velocity, augmentation index, reactive hyperemia index, total vessel density, microvascular flow index, proportion of perfused vessels, vessel diameter distribution, carotid intima-media roughness, strain/strain rate of the common carotid artery/abdominal aorta, echocardiographic dimensions of the heart, left ventricular function (MAPSE, EF, FS, GPLS, E/A, E/E', left ventricular pressure-volume loop and derived efficiency parameters), liver stiffness, liver volume hand grip strength, six-minute walk distance, HDL cholesterol, triglycerides, fasting blood sugar level, GOT, GPT, yGT Caries care status (WHO 2013/ICDAS 2009), Fissure sealant status, MIH status, presence of erosions	—

Measure

Time frame

ED-consumption behaviour, caffeine-consumption behaviour, pre-existing health conditions, Prevalence of adverse physical events, medication/drug use, socioeconomic status, education status, DAST-10 score, WHO-5, sleep duration, sleep quality, MEDAS score, KIDMED score, MET minutes per week, adherence to WHO guidelines on physical activity and sedentary behaviour, screen time Height, weight, waist circumference, lean body mass, Heart rhythm, electrical axis, heart rate, Sokolow-Lyon index, presence of cardiac arrhythmias, systolic/diastolic/central blood pressure, pulse wave velocity, augmentation index, reactive hyperemia index, total vessel density, microvascular flow index, proportion of perfused vessels, vessel diameter distribution, carotid intima-media roughness, strain/strain rate of the common carotid artery/abdominal aorta, echocardiographic dimensions of the heart, left ventricular function (MAPSE, EF, FS, GPLS, E/A, E/E', left ventricular pressure-volume loop and derived efficiency parameters), liver stiffness, liver volume hand grip strength, six-minute walk distance, HDL cholesterol, triglycerides, fasting blood sugar level, GOT, GPT, yGT Caries care status (WHO 2013/ICDAS 2009), Fissure sealant status, MIH status, presence of erosions

—

Countries

Germany

Contacts

Public ContactFelix Sebastian Oberhoffer

Abteilung Kinderkardiologie und Pädiatrische Intensivmedizin LMU Klinikum

Felix.Oberhoffer@med.uni-muenchen.de+49 (0)89 4400 -73942

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026