F50.0
Conditions
Interventions
Group 1: MANTRa (Maudsley Model for Anorexia Nervosa Treatment for Adolescents) is delivered as 40 weekly individual psychotherapy sessions (approximately 50 minutes each). Parents are involved in 8 t
Sponsors
Universitätsklinik für Kinder- und Jugendpsychiatrie, Eating Disorders Care and Research Unit, Medizinische Universität Wien
Eligibility
Sex/Gender
All
Age
13 Years to 21 Years
Inclusion criteria
Inclusion criteria: DSM-5 diagnoses of anorexia nervosa of both subtypes (restrictive / binge purging) and atypical Anorexia Nervosa; sufficient cognitive ability and German language proficiency to understand the questionnaires; willingness to engage in psychotherapy.
Exclusion criteria
Exclusion criteria: Severe comorbid disorder requiring acute treatment (e.g., psychosis, suicidal ideation); pregnancy; life-threatening state of anorexia nervosa requiring immediate inpatient treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI and BMI-SDS (Standard deviation score, sex and age-adjusted): change between baseline (T0) and post-intervention (T2, 12 months); additional assessment time points at T1 (6 months after start of therapy) and T3 (18-months follow-up) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Eating disorder remission (T1, T2, T3) defined according to the DMS-5 (no, partial vs. full remission), as well as by >= 90% expected body weight (EBW) & EDE total score within 1 SD of the community norm - Severity of eating disorder psychopathology: Eating disorder examination interview (EDE) and Eating Disorder Inventory 2 (EDI-2) Questionnaire - Comorbid Psychopathologie (T0, T1, T2, T3): Beck Depression Inventory (BDI-2, Questionnaire), State/Trait Anxiety Inventory (STAI, Questionnaire), Obsessive-compulsive Inventory (OCI-R, Questionnaire) - Comorbid psychiatric diagnoses (T0, T2): Diagnostic Interview for Mental Disorders in Children and Adolescents (Kinder-DIPS, Interview) - Emotion regulation (T0, T2): Self-Report Measure for the Assessment of Emotion Regulations Skills (SEK-27, Questionnaire) - Quality of Life (T0, T2, T3): Inventory for the Assessment of Quality of Life in Children and Adolescents (ILK, Questionnaire) - Acceptability / Satisfaction with treatment (T1, T2): Questionnaire to assess treatment (FBB, Questionnaire) - Therapeutic alliance (T1, T2): Therapeutic Alliance Scale for Children and Adolescents (FTB-KJ, Questionnaire) Additional measures: - Treatment motivation (T0): Questionnaire assessing Therapy Motivation (FBTM40) - Change process factors in psychotherapy (T0, T1, T2): Change Process Questionnaire (CPQ-AN, Questionnaire) | — |
Countries
Austria
Contacts
Public ContactAndreas Karwautz
Universitätsklinik für Kinder- und Jugendpsychiatrie, Eating Disorders Care and Research Unit
Outcome results
None listed