The effect of creatine on cognitive performance during sleep deprivation
Conditions
Interventions
Group 1: Arm 1, intervention group: Single oral supplementation of 0.2 g/kg body weight of the dietary supplement creatine monohydrate following an evening baseline measurement. Participants remain in
Sponsors
Forschungszentrum Jülich
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: At least 18 years of age. A written declaration of consent must be provided
Exclusion criteria
Exclusion criteria: Age over 60 years. -Any medication affecting the study parameters, particularly centrally active drugs and substances. -Kidney disease, renal insufficiency, diabetes, or any evidence of impaired renal function. -Lifetime cumulative intake of nephrotoxic substances in hazardous amounts (e.g., a total of 1 kg of ibuprofen). -Intake of more than 30 g of creatine supplements within the 6 months prior to the measurement. -Intake of any creatine dietary supplements within the 3 weeks prior to the measurement. -Epilepsy; one or more seizures after the age of 12. -Diabetes (already mentioned, but kept for consistency). -Chronic sleep disorders. -Drug addiction, smoking. -Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigation of the effect of acute supplementation with 0.2 g/kg creatine monohydrate, compared with a placebo, on cognitive performance (particularly working memory and executive functions) during 21 hours of acute sleep deprivation. Data will be collected using cognitive tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Analysis of gender-specific differences in the effectiveness of creatine supplementation on cognitive performance under sleep deprivation. 2. Investigation of the correlation between the degree of subjective fatigue and objective test performance in specific task sets | — |
Countries
Germany
Contacts
Public ContactAli Gordjinejad
Forschungszentrum Jülich
Outcome results
None listed