Analysis of acute mastoiditis, sinugenic orbital complications, and oto- and sinugenic central complications before, during and after the COVID-19 pandemic

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039829

Enrollment

430

Registered

2026-05-07

Start date

2026-04-21

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H70

Interventions

Group 1: All patients who underwent surgery performed by the Department of Otorhinolaryngology for mastoiditis, oto- or sinugenic intracranial complications, or sinugenic orbital complications at the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The only inclusion criterion is surgical treatment by the Department of Otolaryngology at the University Hospital Bonn in cases of acute mastoiditis, oto- or sinugenic central complication, or sinugenic orbital complication.

Exclusion criteria

Exclusion criteria: Indication of incorrect coding or recording of an incorrect treatment diagnosis in the computer information system.

Design outcomes

Primary

Measure	Time frame
Primary outcome is the assessment of the pathogen and resistance spectrum of acute mastoiditis, as well as sinugenic orbital complications and oto- and sinugenic central complications. The primary outcome measures are the intraoperative swab results and the detected bacterial strains with their corresponding antibiograms.	—

Secondary

Measure	Time frame
The secondary outcome includes clinical symptoms presented by patients initially or during the course of their illness, such as fever, double vision, visual impairment, or dizziness. Furthermore, the study will examine which imaging modalities were performed (magnetic resonance imaging, computed tomography, and ultrasound) and their corresponding reports. Additional secondary endpoints include patient-specific characteristics such as sex, age, medical history, height, and weight. The study will also collect data on the length and duration of hospital stays, the results of laboratory tests conducted during the hospital stay, and clinical parameters collected during the hospital stay. All complications, such as post-operative bleeding, which were coded separately, will also be analyzed as secondary endpoints.	—

Measure

Time frame

The secondary outcome includes clinical symptoms presented by patients initially or during the course of their illness, such as fever, double vision, visual impairment, or dizziness. Furthermore, the study will examine which imaging modalities were performed (magnetic resonance imaging, computed tomography, and ultrasound) and their corresponding reports. Additional secondary endpoints include patient-specific characteristics such as sex, age, medical history, height, and weight. The study will also collect data on the length and duration of hospital stays, the results of laboratory tests conducted during the hospital stay, and clinical parameters collected during the hospital stay. All complications, such as post-operative bleeding, which were coded separately, will also be analyzed as secondary endpoints.

—

Countries

Germany

Contacts

Public ContactAlexander Philippe Maas

Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Universitätsklinikum Bonn

alexander.maas@ukbonn.de+4915117193715

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026