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Image-based lesion-specific immune classification in oligometastatic disease in potentially heterogeneous longitudinal multicenter imaging and irradiation data

Image-based lesion-specific immune classification in oligometastatic disease in potentially heterogeneous longitudinal multicenter imaging and irradiation data - ImmunRadiomics PM4Onco

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039815
Enrollment
40
Registered
2026-04-14
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oligometastatic tumor disease

Interventions

Group 1: Retrospective analysis of patients who were treated from 01.01.2010 - 28.02.2023 with radiotherapy and followed up in the oligometastatic stage of the disease.

Sponsors

Universitätsklinikum Heidelberg
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with extracranial oligometastatic disease (up to 5 lesions or affected (lymph node) regions) who received ablative radiotherapy for the treatment of oligometastases at the respective centers in the period up to 02/2023.

Exclusion criteria

Exclusion criteria: Patients who did not receive therapy for oligometastatic disease.

Design outcomes

Primary

MeasureTime frame
Establishment of a multicenter cohort with radiation therapy data (RTSTRUCT, RTPLAN, radiation planning CTs), longitudinal imaging data and clinical parameters

Secondary

MeasureTime frame
- Assessment of data heterogeneity / comparability / robustness of analyses on multi-center radiation and imaging data - Longitudinal immunological characterization of individual lesions using the radiomics immune score and association with underlying tumor characteristics and prognosis

Countries

Germany

Contacts

Public ContactMaximilian Knoll

Universitätsklinikum Heidelberg

studienkoordination.rad@med.uni-heidelberg.de+49 6221 56 8202

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026