S06.0
Conditions
Interventions
Group 1: The non-randomized, multicenter, prospective observational study without a control group comprises three main phases: phenotyping/initial assessment after TBI (T1), provision of individualize
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Traumatic brain injury without surgical intervention (Glasgow Coma Scale 13–15), ability to walk more than 10 meters, residence within =50 km of the study center.
Exclusion criteria
Exclusion criteria: Concomitant fractures, severe multimorbidity (e.g., COPD GOLD C/D, NYHA class IV), advanced neurodegenerative diseases, life expectancy <12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study outcomes are the identification of modifiable TBI risk factors at T1: - Mobility impairments, assessed using standardized motor tests, including the 2-Minute Walk Test, the Short Physical Performance Battery, the Timed Up and Go test, and the Rivermead Mobility Index. - Inappropriate medication use, assessed through medication screening with a focus on fall risk–inducing drugs (FRIDs). - Ergonomic issues in the home environment, assessed using the Housing Enabler. Based on these risk factors, corresponding recommendations are derived and discussed with the patients (T2). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include the implementation of the recommendations (which of these were implemented; yes/no), barriers and facilitating factors for implementation (qualitative data), recurrent falls (self-reported), as well as changes in mobility and quality of life (EQ-5D). | — |
Countries
Germany
Contacts
Public ContactAlexander Younsi
Universitäsklinikum Heidelberg
Outcome results
None listed