PeRiOperaTivE CoTinuous vital sign monitoring in non-cardiac surgery patients: the prospective PROTECT registry

PeRiOperaTivE CoTinuous vital sign monitoring in non-cardiac surgery patients: the prospective PROTECT registry - PROTECT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039750

Enrollment

1500

Registered

2026-03-26

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative vital sign abnormalities

Interventions

Group 1: Continuous pre- (48h) and postoperative (72h) vital sign monitoring.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Scheduled intermediate- or high-risk non-cardiac surgery as defined by the 2022 ESC Guidelines on cardiovascular risk assessment - General anesthesia with a planned surgical duration of at least 120 minutes

Exclusion criteria

Exclusion criteria: - Emergency surgery - Contraindications to the viQtor sensor (e.g., severe dermatitis, burns, known allergy to adhesive materials) - Pregnancy - Inability to provide informed consent (e.g., cognitive impairment, language barrier without adequate translation, legal incapacity)

Design outcomes

Primary

Measure	Time frame
The primary aim of this registry is to collect preoperative and postoperative vital signs together with clinical data to investigate the clinical relevance of perioperative vital sign monitoring in patients before and after intermediate- or high-risk non-cardiac surgery. As this is a registry, no primary endpoint is a priori defined.	—

Secondary

Measure	Time frame
• To describe and compare the incidence, duration, and severity of abnormal vital signs obtained using continuous vital sign monitoring in patients before and after intermediate- or high-risk non-cardiac surgery. • To characterize patterns of vital sign abnormalities during daytime versus nighttime periods • To explore associations between preoperative vital sign patterns and postoperative complications • To explore associations between postoperative vital sign patterns and clinical outcomes • To assess the feasibility and patient acceptance of continuous vital sign monitoring in the perioperative setting • To describe the relationship between continuous vital sign data and standard intermittent vital sign measurements • To identify potential early warning patterns that precede clinical deterioration	—

Measure

Time frame

• To describe and compare the incidence, duration, and severity of abnormal vital signs obtained using continuous vital sign monitoring in patients before and after intermediate- or high-risk non-cardiac surgery. • To characterize patterns of vital sign abnormalities during daytime versus nighttime periods • To explore associations between preoperative vital sign patterns and postoperative complications • To explore associations between postoperative vital sign patterns and clinical outcomes • To assess the feasibility and patient acceptance of continuous vital sign monitoring in the perioperative setting • To describe the relationship between continuous vital sign data and standard intermittent vital sign measurements • To identify potential early warning patterns that precede clinical deterioration

—

Countries

Germany

Contacts

Public ContactBernd Saugel

Universitätsklinikum Hamburg-Eppendorf

b.saugel@uke.de+49 40 7410 - 52415

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026