Acute stroke I63
Conditions
Interventions
Group 1: Arm 1: Mobile Stroke Unit (MSU)
Prehospital neurological assessment and acute stroke care delivered by the Mobile Stroke Unit during its operational hours. This includes an initial clinical-n
Sponsors
Neurologische Klinik und Klinik für Radiologie und Nuklearmedizin, Universitätsmedizin Mannheim Universitätsklinikum Mannheim GmbH Medizinische Fakultät Mannheim der Universität Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Suspected acute stroke, identified either by the Integrated Dispatch Center Mannheim or by emergency medical personnel. - Primary care provided in Mannheim either by the Mobile Stroke Unit (MSU) during its operational hours or by the conventional emergency medical service (non-MSU) when the MSU is not available. - Final diagnosis of a cerebrovascular event (e.g., ischemic stroke, intracerebral hemorrhage, transient ischemic attack). - Treatment at the University Medical Center Mannheim with complete clinical baseline documentation.
Exclusion criteria
Exclusion criteria: - No final diagnosis of a cerebrovascular event (e.g., differential diagnoses such as migraine, epileptic seizure without stroke, or hypoglycemia). - No treatment or diagnostic work-up at the University Medical Center Mannheim (no access to complete routine clinical data). - Technically or organizationally incomplete documentation that does not allow assessment of the primary endpoints.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of time-critical process intervals in acute stroke care. The following metrics will be collected in the MSU and will be compared between the MSU and non-MSU groups: Onset-to-Imaging time (time from symptom onset/“last seen well” to first brain imaging), Onset-to-Needle time (time to initiation of intravenous thrombolysis), Onset-to-Groin time (time to arterial puncture for mechanical thrombectomy), Onset-to-Stroke Unit time (time to admission to the Stroke Unit) | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional outcome (Modified Rankin Scale at discharge and at three months), neurological severity (National Institutes of Health Stroke Scale at admission, after treatment, and at discharge), quality of life (patient-reported outcome measures at the three-month follow-up), complication rates (including symptomatic intracranial hemorrhage and other therapy-associated complications), and in-hospital care parameters (length of hospital and ward stay, rate of emergency department bypass), assessed from post-discharge medical records or via telephone follow-up. | — |
Countries
Germany
Contacts
Public ContactCarolin Hoyer
Neurologische Klinik, Universitätsmedizin Mannheim Universitätsklinikum Mannheim GmbH Medizinische Fakultät Mannheim der Universität Heidelberg
Outcome results
None listed