Patients treated with bacteriophages alone or a combination of bacteriophages with other anti-infectives (e.g. antibiotics, antiseptic solutions) or a combination of bacteriophages with other therapeutic interventions (e.g. surgical intervention, probiotics etc.).
Conditions
Interventions
Group 1: Multi-centre, observational, prospective, and retrospective registry. Patients treated with bacteriophages alone or a combination of bacteriophages with other anti-infectives (e.g. antibiotic
Sponsors
Universitätsmedizin Frankfurt, Medizinische Klinik II, Schwerpunkt Infektiologie
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with planned, ongoing, or completed bacteriophage therapy will be included. For prospective pseudonymised data collection, written informed consent must be obtained prior to enrollment.
Exclusion criteria
Exclusion criteria: Patient with any personal or logistical condition which in the opinion of the investigator may interfere with the informed consent process (only applicable in case of prospective pseudonymised inclusion).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the safety and efficacy of bacteriophage therapy alone or with concomitant antibiotics and / or alternative treatment options . Data collection using an electronic case report form (eCRF). | — |
Secondary
| Measure | Time frame |
|---|---|
| - To assess the clinical, sociodemographic, and regional profiles of patients receiving phage therapy. - Identify indications and regional differences in bacteriophage therapy strategies. - Characterise clinical disease patterns leading to phage therapy and evaluate clinical and microbiological outcomes. - To generate data to inform consensus guidelines and healthcare stakeholders - Develop standardized measurement instruments, endpoints, and process/outcome parameters for clinical, microbiological, and patient-reported evaluations. | — |
Countries
Germany
Contacts
Public ContactLene Tscharntke
Universitätsmedizin Frankfurt, Medizinische Klinik II, Schwerpunkt Infektiologie
Outcome results
None listed