F32.1
Conditions
Interventions
Group 1: For this study, inpatient and outpatients with a depressive disorder will be recruited who have been stably adjusted to their medication for at least one week. All participants must be betwee
Sponsors
Klinik für Psychiatrie, Psychotherapie und Psychosomatik
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Sufficient German language proficiency Ability to provide informed consent Voluntary treatment Diagnosis of a depressive episode Stable maintenance medication for at least one week No contraindication to physical exercise No contraindication to cold exposure
Exclusion criteria
Exclusion criteria: Age 65 years Insufficient German language proficiency Inability to provide informed consent Involuntary treatment status Contraindication to physical exercise Pregnancy or suspected pregnancy Existing severe cardiovascular disease requiring ongoing treatment (e.g., poorly controlled hypertension, heart failure, arrhythmias) Cold-induced conditions (e.g., Raynaud’s syndrome, cold urticaria) Acute infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate variability (HRV) will be used as the primary outcome to objectively assess recovery. HRV reflects the balance between parasympathetic and sympathetic activity and is therefore a reliable indicator for measuring recovery after exercise. HRV will be assessed at each of the four measurement time points. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following secondary outcomes will be assessed: Lactate (Lactate Scout) Respiratory rate (manual measurement / chest strap) Fatigue/exhaustion (FSS) Pain perception (NRS) Subjective well-being (WHO-5) Mood (BDI, HAMD, PANAS, PHQ-9) Functional level and quality of life (GAF) Physical activity (IPAQ) Cognitive performance (Trail Making Test A/B) Vital signs (blood pressure monitor, body weight scale) QT variability (exploratory) All parameters will be assessed at each measurement time point. | — |
Countries
Germany
Contacts
Public ContactAnna Hirschbeck
Klinik für Psychiatrie, Psychotherapie und Psychosomatik
Outcome results
None listed