Diagnosis of traumatic or non-traumatic spinal cord injury (i.e. injury of the spinal cord with or without any external physical impact, AIS A, B, C or D)
Conditions
Interventions
Group 1: Patients with acute and chronic spinal cord injury will be assessed once or longitudinally using magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and standard clinical
Sponsors
Medizinische Universität Wien
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: General health, meaning no chronic or persistent diseases, except for a diagnosis of traumatic or non-traumatic spinal cord injury, based on medical history, physical examination and clinical interview Willingness and competence to sign the informed consent form. (For patients only) Diagnosis of traumatic or non-traumatic spinal cord injury (i.e. injury of the spinal cord with or without any external physical impact, AIS A, B, C or D).
Exclusion criteria
Exclusion criteria: Women who are pregnant or breast feeding. Failure to comply with the study protocol or to follow the instruction of the investigating team. Any contraindications for MRI, such as non-MRI-safe metal implants (e.g., pacemakers, metal heart valves, surgical clips, implanted electronic infusion pumps, or similar devices). Claustrophobia. Any other neurological or psychiatric disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantifiable MRI- and MRS-based parameters characterizing structural and biochemical changes in the spinal cord. | — |
Secondary
| Measure | Time frame |
|---|---|
| Association between MRI- and MRS-based parameters and standard clinical neurological examinations. Comparison of MRI and MRS parameters between patients with acute and chronic spinal cord injury and healthy controls. Reproducibility and methodological stability of MRI and MRS parameters across repeated measurements. | — |
Countries
Austria
Contacts
Public ContactTim Max Emmenegger
Medizinische Universität Wien
Outcome results
None listed