Detection of Critical Laboratory Values Using Real-Time Data Streaming in Clinical Routine

Detection of Critical Laboratory Values Using Real-Time Data Streaming in Clinical Routine - DKLED

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00039626

Enrollment

700

Registered

2026-04-07

Start date

2026-03-18

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical laboratory values in critically ill intensive care patients.

Interventions

Group 1: The aim of the proposed research project is to investigate the feasibility of a real-time alert system for the automated identification of critical laboratory values and their timely, structu

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age = 18 years Admission to one of the two intensive care units WD1i or WD2i of the Deutsches Herzzentrum der Charité Analysis of laboratory values for the duration of the patient’s stay in one of the two specified intensive care units Laboratory values collected between 18 March 2026 and 18 June 2026

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Endpoint: Accuracy and feasibility of automated detection of critical laboratory values in real-time clinical data streams. When assessed: Continuously during the observation period 18 March 2026 – 18 June 2026. How data is collected: Automated analysis of mirrored routine laboratory data streams from adult patients treated in two cardiac surgical intensive care units at the Deutsches Herzzentrum der Charité. Critical laboratory values are identified using predefined thresholds. System performance is evaluated by comparison with reference data extracted after the study period.	—

Measure

Time frame

Endpoint: Accuracy and feasibility of automated detection of critical laboratory values in real-time clinical data streams. When assessed: Continuously during the observation period 18 March 2026 – 18 June 2026. How data is collected: Automated analysis of mirrored routine laboratory data streams from adult patients treated in two cardiac surgical intensive care units at the Deutsches Herzzentrum der Charité. Critical laboratory values are identified using predefined thresholds. System performance is evaluated by comparison with reference data extracted after the study period.

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Secondary

Measure	Time frame
Endpoint: Association between the frequency of critical laboratory values and clinical outcomes including in-hospital mortality and indicators of disease severity (e.g., ICU length of stay, ventilation duration, vasopressor therapy). Temporal distribution of critical laboratory values after ICU admission. When assessed: After completion of the study period 18 March 2026 – 18 June 2026. How data is collected: Analysis of routine laboratory data streams combined with additional clinical contextual data retrieved from the Charité Health Data Platform.	—

Measure

Time frame

Endpoint: Association between the frequency of critical laboratory values and clinical outcomes including in-hospital mortality and indicators of disease severity (e.g., ICU length of stay, ventilation duration, vasopressor therapy). Temporal distribution of critical laboratory values after ICU admission. When assessed: After completion of the study period 18 March 2026 – 18 June 2026. How data is collected: Analysis of routine laboratory data streams combined with additional clinical contextual data retrieved from the Charité Health Data Platform.

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Countries

Germany

Contacts

Public ContactTobias Röschl

Charité

tobias.roeschl@dhzc-charite.de+49 30 450 616097

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 10, 2026