Effect of different airway devices in intra-arrest ventilation using the Zoll autopulse NXT

Effect of different airway devices in intra-arrest ventilation using the Zoll autopulse NXT - Intra-Vent-NXT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00039559

Enrollment

Registered

2026-03-09

Start date

2026-03-30

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R09.2 I46

Interventions

Group 1: AuraGain laryngeal mask airway (Ambu) - Bag-device ventilation (BDV) - Volume-controlled ventilation (e.g. IPPV) - Pressure-controlled ventilation (e.g. BIPAP) Group 2: iGel supraglottic airw

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Thiel-fixed body donors: all participants had given consent during their lifetime to the use of their bodies at the anatomical institute or for scientific research.

Exclusion criteria

Exclusion criteria: - Acute respiratory distress syndrome (ARDS) - Severe pulmonary or thoracic injuries - Undrained pneumothorax - Abnormal airways or presence of a tracheostoma - History of severe aspiration

Design outcomes

Primary

Measure	Time frame
Expiratory tidal volume (mL) during mechanical CPR with ventilation via supraglottic airway devices compared to endotracheal intubation under different ventilation modes. The mean, actually applied expiratory tidal volume during the entire 16-minute ventilation period (4 × 4 minutes) under mechanical chest compressions (110/min) is measured. The measurement and recording of the tidal volumes is performed by the ventilator itself and by special flow meters in the ventilation circuit.	—

Measure

Time frame

Expiratory tidal volume (mL) during mechanical CPR with ventilation via supraglottic airway devices compared to endotracheal intubation under different ventilation modes. The mean, actually applied expiratory tidal volume during the entire 16-minute ventilation period (4 × 4 minutes) under mechanical chest compressions (110/min) is measured. The measurement and recording of the tidal volumes is performed by the ventilator itself and by special flow meters in the ventilation circuit.

—

Secondary

Measure	Time frame
1. Assessment of the occurrence of airway injuries depending on the airway device and ventilation mode used. 2. Assessment of the occurrence of lung injuries under the different airway and ventilation strategies. 3. Analysis of process- or CPR-associated injuries in the context of mechanical resuscitation. 4. Investigation of adherence to predefined ventilation parameters under the different airway and ventilation strategies. 5. Analysis of the frequency and type of respiratory alarms depending on the airway device and ventilation mode. 6. Investigation of the effects of the different airway and ventilation strategies on hemodynamic parameters, vascular blood flow, and intracranial pressure.	—

Measure

Time frame

1. Assessment of the occurrence of airway injuries depending on the airway device and ventilation mode used. 2. Assessment of the occurrence of lung injuries under the different airway and ventilation strategies. 3. Analysis of process- or CPR-associated injuries in the context of mechanical resuscitation. 4. Investigation of adherence to predefined ventilation parameters under the different airway and ventilation strategies. 5. Analysis of the frequency and type of respiratory alarms depending on the airway device and ventilation mode. 6. Investigation of the effects of the different airway and ventilation strategies on hemodynamic parameters, vascular blood flow, and intracranial pressure.

—

Countries

Germany

Contacts

Public ContactGerrit Jansen

Universitätsklinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerzmedizin des Johannes Wesling Klinikums Minden

gerrit.jansen@muehlenkreiskliniken.de+4957179054401

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026