The effects of various fascial interventions on myofascial structures and pathopsychological processes in depression

The effects of various fascial interventions on myofascial structures and pathopsychological processes in depression - -

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00039556

Enrollment

240

Registered

2026-04-28

Start date

2024-05-06

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32.0 F32.1 F32.2

Interventions

Group 1: n= 120 adult, inpatient patients with a diagnosis of "Depressive Disorder" This cohort will be randomly divided into three groups for the following interventions: Fascial Intervention 1 "Foa

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Only inpatient patients with a minimum score of 14 on the Beck Depression Inventory (BDI-II) will be admitted to the depressive group. Only participants with a maximum score of 13 on the Beck Depression Inventory (BDI-II) will be admitted to the healthy control group.

Exclusion criteria

Exclusion criteria: Depressive Group: psychotic disorders, bipolar disorders, musculoskeletal disorders, and chronic back pain Healthy Control Group: musculoskeletal disorders and chronic back pain

Design outcomes

Primary

Measure	Time frame
The primary outcome is the stiffness level of the myofascial tissue, measured using a tissue compliance measurement device (IndentoPro) before and after the single intervention.	—

Secondary

Measure	Time frame
Measurement of psychophysiological stress parameters (including electrodermal activity, heart rate, blood volume pulse, heart rate variability, etc.) using a bio- and neurofeedback device (Nexus 10, Biotrace+) before and after the intervention. Self-referential encoding task (SRET; Ramel et al., 2007; adjective list with 10 positive and 10 negative words taken from Williams & Broadbent, 1986) to measure negative memory bias, conducted between the two rounds of interventions and immediately afterward. Positive and Negative Affect Schedule (PANAS; Watson et al., 1988; German version by Krohne et al., 1996) to assess affects after the intervention. Evaluation of credibility and pain after the intervention: To evaluate the credibility of the interventions, study participants will be asked after their completion how logical this intervention seems to them at that moment. They will rate this question on a scale from 1 (not logical at all) to 9 (very logical). Similarly, study participants will retrospectively rate the pain caused by the intervention on a scale from 1 = "no pain at all" to 9 = "very severe pain."	—

Measure

Time frame

Measurement of psychophysiological stress parameters (including electrodermal activity, heart rate, blood volume pulse, heart rate variability, etc.) using a bio- and neurofeedback device (Nexus 10, Biotrace+) before and after the intervention. Self-referential encoding task (SRET; Ramel et al., 2007; adjective list with 10 positive and 10 negative words taken from Williams & Broadbent, 1986) to measure negative memory bias, conducted between the two rounds of interventions and immediately afterward. Positive and Negative Affect Schedule (PANAS; Watson et al., 1988; German version by Krohne et al., 1996) to assess affects after the intervention. Evaluation of credibility and pain after the intervention: To evaluate the credibility of the interventions, study participants will be asked after their completion how logical this intervention seems to them at that moment. They will rate this question on a scale from 1 (not logical at all) to 9 (very logical). Similarly, study participants will retrospectively rate the pain caused by the intervention on a scale from 1 = "no pain at all" to 9 = "very severe pain."

—

Countries

Germany

Contacts

Public ContactMarcus Müller

Pädagogische Hochschule Karlsruhe

mueller03@ph-karlsruhe.de+4915253155028

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026