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Hormonal Influences on Female Performance: A Cross-Sectional and Longitudinal Study of Cognitive, Motor, and Neuromuscular Function Across the Female Lifespan

Hormonal Influences on Female Performance: A Cross-Sectional and Longitudinal Study of Cognitive, Motor, and Neuromuscular Function Across the Female Lifespan

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00039534
Enrollment
98
Registered
2026-03-10
Start date
2026-03-25
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menstrual cycle, premenopause, perimenopause, postmenopause

Interventions

Group 1: Intervention group: working women (aged 25–65) participating in a 12-week health intervention consisting of an exercise programme (twice a week for 45 minutes) and health workshops on nutriti

Sponsors

Technische Universität Chemnitz
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: - Tracking of the menstrual cycle or menopause status, for which cycle documentation has been carried out for at least 3 months using an app or menstruation diary - Native-level German language skills - Written consent to participate in the study and data processing

Exclusion criteria

Exclusion criteria: - Current pregnancy or breastfeeding - Occurrence of acute dizziness, fever, infectious diseases or cold symptoms - Presence of a diagnosed and medically treated mental illness (e.g. major depression) or neurocognitive disorder (e.g. confirmed dementia) - Presence of a neurological disease (e.g. epilepsy, Parkinson's disease) or traumatic brain injury - Suffering from severe cardiovascular system limitations (e.g. heart failure, cardiac arrhythmia) - Impairments of the musculoskeletal system (e.g. immobility, acute pain syndrome, bone diseases, joint replacement), acute injuries to the musculoskeletal system or in the past 6 months - Orthopaedic surgery in the past 6 months - Presence of implanted cardiac electrical devices (e.g. pacemaker/ICD) - Presence of wounds, open skin areas or burns on the upper body in the area of the sternum, upper back or thighs, or skin diseases caused by viruses, fungi or bacteria - Presence of diabetic neuropathy (e.g. diabetic foot syndrome) - Harmful use of or dependence on substances, including alcohol - Presence of speech comprehension disorders

Design outcomes

Secondary

MeasureTime frame
- Body composition using bioimpedance analysis - Menopausal symptoms using the Menopause Rating Scale - Productivity at work using the Work Productivity and Activity Impairment Questionnaire (WPAI:Menopause) - Thermoregulation using infrared thermographic camera and thermosensory perception device - Cognitive performance using Flaker test, Digit Span Forwards & Backwards, Montreal Cognitive Assessment (MoCA) - Muscle function using the sit-to-stand test - Muscle quality using ultrasound of the quadriceps femoris muscle - Maximum isometric hand strength using a hand dynamometer - Physical activity using wearables and the Global Physical Activity Questionnaire (GPAQ) - Sleep quality using wearables and the Pittsburgh Sleep Quality Index questionnaire

Primary

MeasureTime frame
Change in the neuromuscular abilities of women (in 3 subgroups: pre-, peri- and postmenopausal phase) through a 12-week health programme, with isometric strength measurement of the front thigh and hand in combination with electromyography (EMG) as well as dynamic and static balance on the Posturomed in combination with EMG, before and after the 12-week intervention

Countries

Germany

Contacts

Public ContactMelanie Strohbach

Technische Universität Chemnitz

melanie.strohbach@hsw.tu-chemnitz.de+49 371 531-35438

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026