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Estimating the burden of imported infectious diseases in a prospective cohort of returning travelers

Estimating the burden of imported infectious diseases in a prospective cohort of returning travelers

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039488
Enrollment
1000
Registered
2026-03-02
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeling ill after traveling

Interventions

Group 1: This is a monocentric, prospective study in which volunteers returning from travel with respiratory infections and/or fever are recruited. After receiving information about the study and givi

Sponsors

Universitätsklinikum Frankfurt, Institut für medizinische Virologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults over the age of 18 who are capable of giving consent and who have respiratory symptoms and/or fever and/or new skin rashes after traveling outside Europe. Return from a trip to destinations outside the European Union. Symptoms must have started during the trip or no later than 48 hours after return.

Exclusion criteria

Exclusion criteria: Patients under 18 years of age Incapacity to give consent (e.g., due to language barriers or cognitive impairments) Taking oseltamivir/baloxavir since the onset of illness.

Design outcomes

Primary

MeasureTime frame
The primary endpoint is the prevalence of infections with the potential for epidemic spreading in a cohort of up to 1,000 symptomatic travelers returning from abroad.

Secondary

MeasureTime frame
Number of pan-negative POCT and rapid antigen tests and metagenomic sequencing results in pan-negative rapid tests. Number of co-infections in rapid respiratory tests. Virological characteristics of virus isolates with sequence differences from strains circulating here.

Countries

Germany

Contacts

Public ContactSandra Ciesek

Universitätsmedizin Frankfurt, Institut für medizinische Virologie

virologie@unimedizin-ffm.de+49 69 63 01 - 52 19

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026