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Correlation of thyroid hormones with exocrine and endocrine pancreatic function in cystic fibrosis

Correlation of thyroid hormones with exocrine and endocrine pancreatic function in cystic fibrosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039470
Enrollment
186
Registered
2026-03-02
Start date
2026-01-07
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E84

Interventions

Group 1: Retrospective analysis of available thyroid values for Heidelberg CF patients from 1998 to 2025 with regard to the endocrine and exocrine pancreatic function of the patients and the clinical

Sponsors

Universitätsklinikum Heidelberg
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who were in treatment between 1998 and 2025 and participate in the registry study “Establishment of a biobank and DNA bank with registry for patients with cystic fibrosis” (S-370/2011)

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

MeasureTime frame
The neonatal TSH levels of all CF patients participating in our registry study between 1998 and 2025 will be evaluated as endpoints. This will be followed by a comparison of neonatal TSH levels between pancreas-sufficient and pancreas-deficient patients, as well as those who experienced a secondary rebound in fecal pancreatic elastase levels and those who did not.

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026