This study examines dietary protein intake in adults aged = 60 years depending on their diet.
Conditions
Interventions
Group 1: Long-term vegan diet prior to study inclusion (= 1 year)
Group 2: Long-term lacto-ovo-vegetarian diet prior to study inclusion (= 1 year)
Group 3: Long-term omnivorous/mixed diet prior to stu
Sponsors
Klinik für Innere Medizin II - Unizentrum Naturheilkunde
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: o Age =60 years o ability to give informed consent o sufficient knowledge of the German language to complete a questionnaire in German language and to understand the study procedures and instructions in German o The ability to prepare meals independently and to eat meals without the help of others o Adherence to an omnivorous/mixed diet, vegetarian diet, or vegan diet for at least one year without interruption. The three groups to be studied are defined by the study protocol as follows: Mixed/omnivorous diet: Contains foods from at least one of the following food groups: meat, fish or seafood, dairy products. Vegetarian diet: Contains neither meat nor fish, but includes foods from at least one of the following food groups: dairy products, eggs, honey. Vegan diet: Contains neither meat nor fish nor dairy products nor eggs.
Exclusion criteria
Exclusion criteria: o Acute or chronic health conditions / illnesses, which, in the opinion of the study director, preclude participation in the study (e.g., acute or chronic infections, oxygen requirements, cancers requiring ongoing treatment, severe autoimmune diseases, dementia, Parkinson's disease, substantial limitations in mobility) o Insufficient German language skills to understand the participant information and the purpose of the study o Nicotine abuse (daily cigarette consumption) o Severe eating disorders, underweight (BMI =18.5 kg/m²) or obesity (BMI =30 kg/m²) o Alcohol abuse (>30g/day) o Participation in another clinical trial within the last four weeks o Known kidney disease with proteinuria (=1 g/day)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dietary protein intake from foods based on a 3-day weighed food diary. Mean protein intake (in g/d) will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. | — |
Secondary
| Measure | Time frame |
|---|---|
| o Mean intake of other macro- and micronutrients (in mg/d or g/d) based on a 3-day weighed food diary. Mean intakes will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. o PRAL (Potential Renal Acid Load), UPRAL (Urinary Potential Renal Acid Load), and NEAP ??(Net Endogenous Acid Production) as estimates of the dietary acid load based on 3-day weighed food intake records (mean in mEq/d) or 24-hour urine collection (UPRAL). Mean values will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. o Urea nitrogen and protein excretion in 24-hour urine collection (mean in g/24h). Mean values will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. o Dynanometer-based non-invasive handgrip strength measurements (in kg). Mean values will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. o Measurement of the fat-free mass (in %) using bioimpedance analysis (BIA). Mean values will be compared between the omnivorous, the lacto-ovo-vegetarian and the vegan diet group. | — |
Countries
Germany
Contacts
Public ContactMaximilian Storz
Klinik für Innere Medizin II - Unizentrum Naturheilkunde
Outcome results
None listed