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Functional/Dissociative Seizures (FDS): Neurobiological, Emotional, and Stress-Related Factors and Approaches to Optimizing Care

Functional/Dissociative Seizures (FDS): Neurobiological, Emotional, and Stress-Related Factors and Approaches to Optimizing Care - NEBEL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039423
Enrollment
120
Registered
2026-03-10
Start date
2026-02-25
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F44.5

Interventions

Group 1: Participation in quantitative and qualitative structured interviews, psychometric assessments, smartphone-based assessments as well as analysis of available clinical findings (cMRI, EEG, labo

Sponsors

LMU Klinikum
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Capacity to provide informed consent Confirmed or suspected diagnosis of functional/dissociative seizures (FDS) or confirmed diagnosis of epilepsy Sufficient proficiency in the German language

Exclusion criteria

Exclusion criteria: Acute florid psychosis Severe cognitive impairment Lack of capacity to provide informed consent Severe neurological disorders with substantial diagnostic uncertainty Acute substance intoxication or manifest substance dependence Medically unstable patients

Design outcomes

Primary

MeasureTime frame
Identification and characterization of somatic, psychiatric, and psychosocial influencing factors in FDS compared to epileptic seizures, and differentiation of potential FDS subtypes (single cross-sectional assessment with the option of longitudinal follow-up after 12 and 24 months)

Secondary

MeasureTime frame
Seizure frequency Psychological symptom burden (e.g., depression, anxiety, dissociation, quality of life) Retinal parameters (Optical Coherence Tomography, OCT) pre- and post-ictal Ecological Momentary Assessment (EMA) based stress and early warning patterns Diagnostic acceptance and subjective coping with the disorder Impact of emergency wristbands on perceived safety and hospitalizations

Countries

Germany

Contacts

Public ContactLukas Stütz

Klinik und Poliklinik für Psychiatrie und Psychotherapie, LMU Klinikum

lukas.stuetz@med.uni-muenchen.de+4989440053370

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026