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Investigation of neuronal effects of yoga-based breathing styles on the human brain and the autonomic stress response

Investigation of neuronal effects of yoga-based breathing styles on the human brain and the autonomic stress response

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00039396
Enrollment
100
Registered
2026-02-26
Start date
2021-05-08
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress

Interventions

Group 1: intervention group: daily performed sequence of 20-minute-long nasal yoga-based respiratory exercises (duration of intervention four weeks) Group 2: active control group: same daily performed

Sponsors

Universitätsklinikum des Saarlandes
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Healthy, most importantly, absence of debilitating neuropsychiatric, cardiovascular, bronchopulmonary diseases, warranting treatment and altering the functionality of said bodily systems. • No significant experience in the field of meditative and\or physical disciplines centring around breath control, e.g. most types of yoga. • No intention to introduce major changes to one’s routine, esp. activities related to sports, breath exercises and\or meditation, for the entire duration of the intervention. • Signing the written consent form (see Appendix). • Explicitly consenting to be notified about accidental findings.

Exclusion criteria

Exclusion criteria: We strictly excluded: • Any bearer of MRI-incompatible body implants, such as pacemakers, drug pumps, cochlear implants, braces (except for retainers), screws, contraceptive coils etc. • Epileptic patients. A more lenient person-to-person approach was implemented in subjects with • A history of surgeries concerning the neurosurgical, thoracic or cardiovascular fields, • Claustrophobia, • Known pregnancy.

Design outcomes

Primary

MeasureTime frame
Detection of neuromorphological changes in the brain using structural MRI (VBM analysis) with 3 measurement points (T1 on day 0, T2 on day 14, T3 on day 28)

Secondary

MeasureTime frame
Evidence of a decrease in physical stress parameters (salivary cortisol, heart rate, blood pressure) based on multiple averaged measurements over 3 measurement days (T1 on day 0, T2 on day 14, T3 on day 28)

Countries

Germany

Contacts

Public ContactChristoph Krick

Klinik für diagnostische und interventionelle Neuroradiologie am Universitätsklinikum des Saarlandes (UKS)

christoph.krick@uks.eu?+49 6861 16 24359 ?

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026