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Bertolotti syndrome - Prospective study of CT-guided resection of an assimilation joint in the lumbosacral junction

Bertolotti syndrome - Prospective study of CT-guided resection of an assimilation joint in the lumbosacral junction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039311
Enrollment
80
Registered
2026-05-06
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bertolotti Syndrome

Interventions

Group 1: Patients with Bertolotti syndrome who have an assimilation joint are examined pre- and postoperatively using the German Pain Questionnaire, Oswestry Disability Index (ODI), Roland and Morris

Sponsors

Uniklinik RWTH Aachen, Klinik für Neurochirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Diagnosis of Bertolotti syndrome: Confirmation of the anatomical abnormality using imaging techniques such as X-ray, CT, or MRI. • Symptomatic presentation: Patients exhibit significant symptoms associated with Bertolotti syndrome, e.g., chronic back pain, sciatica, or neurological symptoms. • Failure of conservative treatments: Non-surgical treatment methods (e.g., physical therapy, pain therapy) have not provided sufficient relief of symptoms, and trial infiltration of the assimilation joint has shown a >50% improvement in symptoms. • Age and general health: Patients over 18 years of age with a health condition that allows surgery • Consent for CT-guided resection of the assimilation joint as part of routine clinical practice.

Exclusion criteria

Exclusion criteria: • Lack of symptomatic presentation: Patients who do not exhibit significant symptoms associated with Bertolotti syndrome. • Inadequate conservative treatment: If insufficient time has been invested in conservative treatments (e.g., physical therapy, pain therapy, or infiltrations). • Presence of serious comorbidities: e.g., severe cardiovascular disease with significantly increased surgical risks. • Neurological deficits: Pre-existing neurological diseases or deficits that are independent of Bertolotti syndrome. • Age and general health: advanced age or poor general health. • Missing consent to the questionnaire survey • Mental illness: existing mental illness that could impair understanding or consent to surgery. • Unrealistic expectations: Patients who have unrealistic expectations of the outcome of assimilation joint resection or who are unwilling to comply with postoperative check-ups will be excluded.

Design outcomes

Primary

MeasureTime frame
Pain reduction, measured using the VAS, by >50% compared to preoperative findings three months postoperatively.

Secondary

MeasureTime frame
Functional improvement three months postoperatively. Assessment of physical function using the ODI and RMDQ to measure the impact on daily activities.

Countries

Germany

Contacts

Public ContactChristian-Andreas Müller

Uniklinik RWTH Aachen, Klinik für Neurochirurgie

camueller@ukaachen.de02418088481

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026