Effects of Lactobacillus reuteri DSM 17938 on the acute psychological, endocrine and immunological stress response in healthy urbans

Effects of Lactobacillus reuteri DSM 17938 on the acute psychological, endocrine and immunological stress response in healthy urbans - NatBed

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00039159

Enrollment

Registered

2026-01-29

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy participants

Interventions

Group 1: Subjects who grew up in an urban area without pets and received a daily oral dose of L. reuteri DSM 17938 for 8 +/-2 weeks. Assessment of proinflammatory and anti-inflammatory responses, both

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: BMI between 19 and 30; grew up in a large city (>40,000 inhabitants) without a pet (dog, cat) until the age of 15

Exclusion criteria

Exclusion criteria: current infections; chronic affective or somatic disorders; smoking; competitive athletes; acute exercise within 24h before blood draws; drug taking (NSAID, cannabis, etc.); acutely (within the last 6 months) bereaved or divorced

Design outcomes

Primary

Measure	Time frame
plasma cytokine and stress hormone secretion pattern in repsonse to TSST Test	—

Secondary

Measure	Time frame
in vitro cytokine production by peripheral blood mononuclear cells (PBMCs) during concanavalin A or lipopolysaccheride (LPS) stimulation	—

Countries

Germany

Contacts

Public ContactStefan Reber

Universitätsklinikum Ulm, Klinik für Psychosomatische Medizin und Psychotherapie

stefan.reber@uni-ulm.de0731/500-61943

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 29, 2026