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Implementation of a structured assessment of myocardial thickening - the "thick Cologne Hearts" clinic

Implementation of a structured assessment of myocardial thickening - the "thick Cologne Hearts" clinic

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00039143
Enrollment
1000
Registered
2026-02-02
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myocardial hypertrophy I42.1 I42.2 I11.0 E85.3

Interventions

Group 1: Patients with cardiological symptoms, thickened interventricular septum on echocardiography and unclear underlying cause after general cardiological evaluation will undergo extended structred

Sponsors

Klinik III für Innere Medizin, Herzzentrum, Universitätsklinik Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: cardiological symptoms thickening of interventrucular septum (>12mm?, >11mm?) in echo underlying disease/cause unclear after initial evaluation

Exclusion criteria

Exclusion criteria: lack of consent

Design outcomes

Primary

MeasureTime frame
Portion (%) of patients with definitive diagnosis of an underlying disease at the end of a structered assessment including history, ECG, laborratory tests and imaging

Secondary

MeasureTime frame
1. Frequency distribution of causes of myocardial thickening in a cardiological realworld cohort - n (%) of underlying diseases 2. n (%) of patients with final diagnosis of transthyretin cardiomyopathy according to disease stages NAC I-II-III, compared to a historical cohort of the hospital from years 2022-2024 3. Accuracy of red flags from the literature for prediction of diagnosis of cardiac amyloidosis

Countries

Germany

Contacts

Public ContactRoman Pfister

Klinik III für Innere Medizin, Herzzentrum, Universitätsklinik Köln

roman.pfister@uk-koeln.de+4922147832495

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026