Prospective randomised study of different surgical techniques to prevent postoperative lymphoceles after robot-assisted laparoscopic radical prostatectomy and their impact on peri- and postoperative morbidity and quality of life

Prospective randomised study of different surgical techniques to prevent postoperative lymphoceles after robot-assisted laparoscopic radical prostatectomy and their impact on peri- and postoperative morbidity and quality of life - Influences of different surgical techniques on the development of postoperative lymphoceles after robotic-assisted laparoscopic prostatectomy (RALP)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00039135

Enrollment

800

Registered

2026-01-29

Start date

2026-02-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer / Lymphadenectomy C61

Interventions

Group 1: -Use of clips to close lymph vessels -Use of a peritoneal flap to cover the lymphadenectomy area Group 2: -Use of clips to close lymph vessels -Use of a Tabotamp patch to cover the lymphadene

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with prostate cancer 2. Robot-assisted radical prostatectomy (RALP) possible 3. Simultaneous lymphadenectomy 4. Capable of giving consent, willing to give consent

Exclusion criteria

Exclusion criteria: 1. Multimodal therapeutic concept 2. No consent 3. Individual decision by the patient and/or surgeon not to perform/have lymphadenectomy performed as part of RALP 4. Contraindication to LAD

Design outcomes

Primary

Measure	Time frame
-Number of lymphoceles (in [ml]) collected in the small pelvis postoperatively (day 5-7).	—

Secondary

Measure	Time frame
-Lymphoceles (in [ml]) at follow-up due to side effects/complications directly/indirectly related to the operation, as well as planned follow-up within the first year after surgery (no study-related visits) -Quality of life (QoL, SF-12 questionnaire) postoperatively (days 5- 7) -Pain perception (VAS pain scale) postoperatively (days 1, 2, 3 and upon discharge) -Drainage duration (in days) and drainage volume (in [ml]) during hospitalisation until final drainage removal -Association of lymphoceles with possible risk factors (number of lymph nodes removed, body mass index, anti-hormonal therapy, previous inguinal hernia repair, etc.) -Length of hospital stay (in days) -Type and number of side effects/complications and development of symptomatic lymphoceles during the inpatient stay and at follow-up within the first postoperative year	—

Measure

Time frame

-Lymphoceles (in [ml]) at follow-up due to side effects/complications directly/indirectly related to the operation, as well as planned follow-up within the first year after surgery (no study-related visits) -Quality of life (QoL, SF-12 questionnaire) postoperatively (days 5- 7) -Pain perception (VAS pain scale) postoperatively (days 1, 2, 3 and upon discharge) -Drainage duration (in days) and drainage volume (in [ml]) during hospitalisation until final drainage removal -Association of lymphoceles with possible risk factors (number of lymph nodes removed, body mass index, anti-hormonal therapy, previous inguinal hernia repair, etc.) -Length of hospital stay (in days) -Type and number of side effects/complications and development of symptomatic lymphoceles during the inpatient stay and at follow-up within the first postoperative year

—

Countries

Germany

Contacts

Public ContactMathias Reichert

Klinik für Urologie Universitätsmedizin Göttingen

mathias.reichert@med.uni-goettingen.de+49 551/39-68141

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026